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Postion:Product Catalog >API>Synthetic Anti-infective Drugs>Natural source of Anti-infectives>Matrine
Matrine
  • Matrine

Matrine NEW

Price $36 $53 $74
Package 25mg 50mg 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Matrine CAS No.: 519-02-8
Purity: 97.16% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameMatrine
DescriptionMatrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.
In vitroIn human non-small cell lung cancer A549 and hepatocellular carcinoma SMMC-7721 cells, Matrine inhibits cell growth. Particularly, in A549 cells, Matrine induces apoptosis by reducing the Bcl-2 / Bax protein ratio.
In vivoIn mice, the median lethal dose (LD50) of Matrine administered via intraperitoneal injection is 157 mg/kg.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationEthanol : 49 mg/mL (197.29 mM)
H2O : 11 mg/mL (44.29 mM), Heating is recommended.
DMSO : 45 mg/mL (181.18 mM)
KeywordsFerroptosis | Inhibitor | anti-oxidative stress | Mitochondrial Autophagy | alpha-Matrine | Apoptosis | Mitophagy | A549 cells | acute kidney injury (AKI) model | Non-small cell lung cancer | hepatoma | Autophagy | Opioid Receptor | Matrine | inhibit | a-Matrine
Inhibitors RelatedHydroxychloroquine | Guanidine hydrochloride
Related Compound LibrariesBioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Drug Repurposing Compound Library | Natural Product Library for HTS | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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