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Postion:Product Catalog >Biochemical Engineering>Inhibitors>PI3K / Akt / mTOR>S6 Kinase Inhibitors>LY-2584702 tosylate salt
LY-2584702 tosylate salt
  • LY-2584702 tosylate salt

LY-2584702 tosylate salt NEW

Price $31 $44 $72
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: LY-2584702 tosylate salt CAS No.: 1082949-68-5
Purity: 98.5% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameLY-2584702 tosylate salt
DescriptionLY-2584702 tosylate salt, a selective ATP-competitive p70S6K inhibitor, is being used in clinical trials for cancer treatment.
In vitroIn HCT116 colon cancer cells, LY2584702 inhibits phosphorylation of the S6 ribosomal protein (pS6) with IC50 of 0.1-0.24 μM. [1] LY2584702 has significant synergistic effects when combined with EGFR inhibitor erlotinib or with the mTOR inhibitor everolimus. [2]
In vivoLY2584702 (12.5 mg/kg BID), demonstrates significant antitumor efficacy in both U87 mg glioblastoma and HCT116 colon carcinoma xenograft models. [1]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationEthanol : < 1 mg/mL (insoluble or slightly soluble)
DMSO : 12 mg/mL (19.43 mM), Sonication is recommended.
KeywordsLY 2584702 | inhibit | S6K | LY2584702 | LY 2584702 Tosylate | LY-2584702 | Inhibitor | LY 2584702 tosylate salt | LY2584702 tosylate salt | LY2584702 Tosylate | LY-2584702 Tosylate | Ribosomal S6 Kinase (RSK)
Inhibitors RelatedQuercitrin | CHIR-98014 | H-89 dihydrochloride | AD80 | BI-D1870 | Bimiralisib | MBM-55S | A-443654 | Prexasertib dihydrochloride | FMK | CYC-116 | Sodium salicylate
Related Compound LibrariesBioactive Compound Library | Pain-Related Compound Library | Kinase Inhibitor Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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