Product Details
Product Name:
LUF6096 |
CAS No.:
1116652-18-6 |
Purity:
100% |
Supply Ability:
10g |
Release date:
2024/11/13 |
Product Introduction
Bioactivity
名稱 | LUF6096 |
描述 | LUF6096 (CF-602) is a potent allosteric enhancer of the adenosine A3 receptor, exhibiting the capability to enhance agonist binding allosterically while demonstrating low orthosteric affinity across adenosine receptors. It displays protective effects in myocardial ischemia/reperfusion injury. |
體外活性 | LUF6096 (10 μM; 30-120 min) reduces the dissociation rate of 125I-AB-MECA from the A3 receptor by 2.5 times in CHO cell membranes and, when pretreated for 15 min, significantly enhances the intrinsic activity of Cl-IB-MECA in inhibiting forskolin-stimulated cAMP production in CHO cells[1]. |
體內(nèi)活性 | LUF6096 (twice i.v. bolus at 0.5 mg/kg or single i.v. bolus at 1 mg/kg) protects against myocardial ischemia/reperfusion injury in dogs[1]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 40 mg/mL (96.54 mM), Sonication is recommended.
|
關(guān)鍵字 | CF 602 | LUF-6096 | LUF6096 | LUF 6096 | CF602 |
相關(guān)產(chǎn)品 | Theophylline monohydrate | Diphylline | Acefylline | Nitrobenzylthioinosine | Aminophylline | Inosine | Theobromine | Istradefylline | Theophylline | Adenosine antagonist-1 | Doxofylline | FK-453 |
相關(guān)庫 | 經(jīng)典已知活性庫 | 神經(jīng)信號分子庫 | 膜蛋白靶向化合物庫 | 神經(jīng)遞質(zhì)受體化合物庫 | 已知活性化合物庫 | GPCR靶點(diǎn)分子庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |