LPA1 receptor antagonist 1 NEW
| Price | $147 | $367 | $587 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-15 |
Product Details
| Product Name: LPA1 receptor antagonist 1 | CAS No.: 1396006-71-5 |
| Purity: 99.58% | Supply Ability: 10g |
| Release date: 2024/11/15 |
Product Introduction
Bioactivity
| 名稱 | LPA1 receptor antagonist 1 |
| 描述 | LPA1 receptor antagonist 1(LPA1 R antagonist 1) is a selective and potent lysophosphatidic acid (LPA1) receptor antagonist (IC50 : 25 nM) for the study of idiopathic pulmonary fibrosis. |
| 體外活性 | Compared to Ki16425 and AM095, LPA1 receptor antagonist 1 demonstrates superior anti-proliferative activity. It exhibits the highest selectivity for LPA1 and efficiently inhibits LPA-induced NHLF proliferation and contraction[1]. Similarly, LPA1 receptor antagonist 1 (compound 2) shows highly specific inhibitory activity against LPA1, with minimal inhibition of LPA3 even at relatively high concentrations.[1]. |
| 體內(nèi)活性 | Oral administration of LPA1 receptor antagonist 1 (compound 2) to mice led to a dose-dependent reduction in plasma histamine levels in a murine LPA challenge model [1]. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 關(guān)鍵字 | LPA1 receptor antagonist 1 | LPA-1 receptor antagonist 1 | LPA1 antagonist 1 |
| 相關(guān)產(chǎn)品 | Radioprotectin-1 | DBIBB | AM966 | Ki16198 | Tetradecyl Phosphonate | LPA2 antagonist 2 | GRI977143 | UCM-05194 | H2L5186303 | Ki16425 |
| 相關(guān)庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 已知活性化合物庫 | GPCR靶點(diǎn)分子庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $2500.00/100mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-10-23 | |
| $0.00/1mg |
VIP1Y
|
Hubei Chuchang Biotech Co., Ltd.
|
2024-04-17 |
United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY