Benzocaine Description:

Benzocaine is a fat-soluble topical anesthetic. Compared with several other local anesthetics such as lidocaine, tetracaine, etc., the intensity of action is small. Comfortable due to its action in the mucous membranes. It is a highly lipid-soluble drug, so it is easy to bind to the lipid layer of mucous membranes or skin, but it is not easy to pass through the human body to produce toxicity.

Benzocaine is the precursor material of imitation urso, o-caine and procaine. At the same time, it is used as a local anesthetic in medicine, has analgesic and antipruritic effects, and is mainly used for narcotic pain and itching of wounds, ulcers, mucosal surfaces and hemorrhoids. The ointment can also be used for pain relief and lubrication during nasopharyngeal catheterization and PEEP endoscopic procedures. Temporarily relieves pain and itching from minor burns, sunburns, trauma and insect bites. Ear is used to relieve pain and itching in acute congestive, concentrated otitis media, swimming and topical. It is also effective for toothache, sore throat, oral ulcers, hemorrhoids, anal fissures, and vulva. Acts as a male genital desensitizer, slows ejaculation. Or as a lubricant for catheter and endoscopic anesthesia.

Use of Benzocaine:

 Benzocaine shares a co-receptor with all other local anesthetics (LAs) in voltage-gated Na+ channels, with an IC50 of 0.8 mM tested with a potential of +30 mV.