Loperamide hydrochloride NEW
Price | Get Latest Price | ||
Package | 1KG | 5KG | 25KG |
Min. Order: | 1KG |
Supply Ability: | 20 T each week |
Update Time: | 2023-08-11 |
Product Details
Product Name: Loperamide hydrochloride | CAS No.: 34552-83-5 |
EC-No.: 252-082-4 | Min. Order: 1KG |
Purity: 98%~99% | Supply Ability: 20 T each week |
Release date: 2023/08/11 |
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Product Name: | Loperamide hydrochloride |
Synonyms: | 4-(4-(p-chlorophenyl)-4-hydroxy-1-piperidyl)-n,n-dimethyl-2,2-diphenylbutyra;4-(p-chlorophenyl)-4-hydroxy-n,n-dimethyl-alpha,alpha-diphenyl-1-piperidine;blox;butyramidehcl;dissenten;fortasec;imodium;imosec |
CAS: | 34552-83-5 |
MF: | C29H34Cl2N2O2 |
MW: | 513.5 |
EINECS: | 252-082-4 |
Product Categories: | IMODIUM;Other APIs;ACTIVE PHARMACEUTICAL INGREDIENTS;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labeled Compounds;Opioid receptor and opioid-like receptor;Amines;Heterocycles;34552-83-5 |
Mol File: | 34552-83-5.mol |
Loperamide hydrochloride Chemical Properties |
Melting point | 223-225°C |
density | 1.1905 (rough estimate) |
refractive index | 1.6100 (estimate) |
storage temp. | 2-8°C |
solubility | Slightly soluble in water, freely soluble in ethanol (96 per cent) and in methanol. |
form | neat |
pka | 8.66(at 25℃) |
color | White to Almost white |
Merck | 14,5571 |
CAS DataBase Reference | 34552-83-5(CAS DataBase Reference) |
Safety Information |
Hazard Codes | T |
Risk Statements | 25 |
Safety Statements | 45 |
RIDADR | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
RTECS | TM4960000 |
HazardClass | 6.1(b) |
PackingGroup | III |
HS Code | 29333990 |
Toxicity | LD50 in mice (mg/kg): 75 s.c.; 28 i.p.; 105 orally; in rats (mg/kg): 185 orally (Niemegeers) |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
Loperamide hydrochloride Usage And Synthesis |
Chemical Properties | White Solid |
Originator | Imodium,Janssen,UK,1975 |
Uses | Labeled Loperamide, which is used as an antidiarrheal |
Uses | Ca channel blocker |
Uses | Loperamide hydrochloride is a Ca2+ channel protein inhibitor and MOR activator. |
Indications | Loperamide hydrochloride (Imodium) structurally resembles both haloperidol and meperidine. In equal doses, loperamide protects against diarrhea longer than does diphenoxylate. It reduces the daily fecal volume and decreases intestinal fluid and electrolyte loss. Loperamide produces rapid and sustained inhibition of the peristaltic reflex through depression of longitudinal and circular muscle activity.The drug also possesses antisecretory activity, presumably through an effect on intestinal opioid receptors. |
Definition | ChEBI: A hydrochloride obtained by combining loperamide with one equivalent of hydrochloric acid. Used for treatment of diarrhoea resulting from gastroenteritis or inflammatory bowel disease. |
Company Profile Introduction
Shandong Huisheng Import & Export Co., Ltd. is located in Jinan city, Shandong Province, is a collection of domestic trade, international trade in one of the diversified services company. Our goal is to provide customers with high quality solutions and one-stop purchasing experience. At present, the company business scope involves five areas: Organic chemical raw materials, inorganic chemical raw materials, fine chemical raw materials, dangerous chemicals and green environmental protection chemical technology project promotion, and we has also established good relations of cooperation with several well-known enterprises and won the strong support of extensive trust from the new and old customers.
Products are widely used in automobile, household appliances, office supplies, mobile phone accessories, routers, food, medical and other fields. At present, our business covers 30 countries, and our customers mainly come from Australia, New Zealand, Canada, Germany, France, Poland, South Korea, Russia, Bangladesh, Vietnam, Kazakhstan, India, Ghana, Nigeria, South Africa, Egypt and other more than 30 countries.
The company has a sound quality management system and advanced professional equipment, with a positive attitude to meet the changing needs of customers. We take "quality products, quality service, competitive price, timely delivery" as the purpose, looking forward to greater cooperation with overseas customers on the basis of mutual benefit.
Our company provides a wide range of products to meet your various needs. Since its inception, the company has always adhered to the "quality first, customer first, reputation first" business policy, wholeheartedly meet the potential needs of our customers. Under the irresistible situation of economic globalization, our company is willing to cooperate sincerely with enterprises around the world to achieve a win-win situation.
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- Since: 2020-11-16
- Address: Room 202-9, Building 1, Evergrande Huafu, Dongying Road, Huaiyin District, Jinan City, Shandong Prov
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