LM11A-31 dihydrochloride NEW
Price | $38 | $82 | $121 |
Package | 10mg | 25mg | 50mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-14 |
Product Details
Product Name: LM11A-31 dihydrochloride | CAS No.: 1243259-19-9 |
Purity: ≥98% | Supply Ability: 10g |
Release date: 2024/11/14 |
Product Introduction
Bioactivity
名稱 | LM11A-31 dihydrochloride |
描述 | LM11A-31 dihydrochloride is a water-soluble, non-peptide with high blood-brain barrier permeability.LM11A-31 dihydrochloride, a p75NTR (neurotrophin receptor p75) Ligand, is a potent proNGF (nerve growth factor) antagonist. |
體內(nèi)活性 | LM11A-31 (orally; 50 or 75 mg/kg) administered for 3 months starting at 6-8 months of age prevents and/or reverses atrophy of basal forebrain cholinergic neurites and cortical dystrophic neurites in mid-stage male APPL/S mice[2].?LM11A-31 (oral gavage;?50 mg kg/day for 4 weeks) significantly mitigates proNGF accumulation and preserves BRB integrity[1]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | H2O : 125 mg/mL (395.23 mM), Sonication is recommended. |
關鍵字 | cholinergic | proNGF | Inhibitor | inhibit | LM11A-31 | growth | dystrophy | disease | p75 | Neurotensin Receptor | LM-11A-31 dihydrochloride | nerve | neurite | receptor | barrier | neurotrophin | factor | Ligand | LM11A 31 dihydrochloride | blood-brain | LM11A31 dihydrochloride | Alzheimer's | p75NTR | LM11A-31 Dihydrochloride |
相關庫 | 經(jīng)典已知活性庫 | 藥物功能重定位化合物庫 | 血腦屏障通透化合物庫 | 抑制劑庫 | NO PAINS 化合物庫 | 口服活性化合物庫 | 臨床期小分子藥物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
Product name | Price | Suppliers | Update time | |
---|---|---|---|---|
$0.00/200kg |
VIP1Y
|
Qingdao RENAS Polymer Material Co., Ltd.
|
2024-07-19 | |
$60.00/1box |
VIP1Y
|
hebei hongtan Biotechnology Co., Ltd
|
2024-03-14 | |
$32.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-14 | |
$38.00/10mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-14 | |
$1.00/1KG |
VIP5Y
|
Career Henan Chemical Co
|
2020-01-18 |
- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY