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Postion:Product Catalog >LGD-6972
LGD-6972
  • LGD-6972

LGD-6972 NEW

Price $81 $197 $289
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: LGD-6972 CAS No.: 1207989-09-0
Purity: 99.33% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameLGD-6972
DescriptionLGD-6972 is an antagonist of glucagon receptor.
In vivoLGD-6972 is well tolerated at the doses tested without dose-related or clinically meaningful changes in clinical laboratory parameters. No subject experiences hypoglycaemia.LGD-6972 has linear plasma pharmacokinetics consistent with once daily dosing that is comparable in healthy and T2DM subjects.?Dose-dependent decreases in fasting plasma glucose are observed in all groups with a maximum of 3.15 mM (56.8 mg/dL) on day 14 in T2DM subjects.?LGD-6972 also reduces plasma glucose in the postprandial state.?Dose-dependent increases in fasting plasma glucagon are observed, but glucagon levels decrease and insulin levels increase after an oral glucose load in T2DM subjects.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 31 mg/mL (44.10 mM)
KeywordsInhibitor | hyperglycaemia | GCGR | Diabetes | cAMP | glucagon | LGD 6972 | LGD6972 | LGD-6972 | inhibit | Glucagon Receptor
Inhibitors RelatedTirzepatide Acetate(2023788-19-2 free base) | PF-06882961 Tris | L-168049 | PF-06882961 | Glucagon (1-29), bovine, human, porcine hydrochloride | (S, R)-LSN 3318839 | NNC 92-1687 | Adomeglivant | 6α-Methylprednisolone 21-hemisuccinate sodium salt | Orforglipron | LSN3318839 | HAEGTFT acetate(926018-95-3 free base)
Related Compound LibrariesBioactive Compound Library | Membrane Protein-targeted Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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