Levomenol NEW
| Price | $110 |
| Package | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-14 |
Product Details
| Product Name: Levomenol | CAS No.: 23089-26-1 |
| Purity: 95% | Supply Ability: 10g |
| Release date: 2024/11/14 |
Product Introduction
Bioactivity
| 名稱 | Levomenol |
| 描述 | Levomenol ((-)-α-BISABOLOL) is a sesquiterpene alcohol that has been found in the essential oils of several aromatic plants, with exerts antioxidant, anti-inflammatory, and anti-apoptotic activities. |
| 體外活性 | Levomenol was able to activate a programmed cell death process in the promastigote stage of the parasite.It causes phosphatidylserine externalization and membrane damage.Moreover, it decreases the mitochondrial membrane potential and total ATP levels.These results highlight the potential use of Levomenol against both L. amazonensis and L. infantum, and further studies should be undertaken to establish it as novel leishmanicidal therapeutic agents[1]. |
| 體內(nèi)活性 | Levomenol inhibits the growth of L. amazonensis promastigotes and amastigotes (IC50s = 8.07 and 4.29 μg/ml, respectively). It also reduces the growth of L. infantum and L. donovani amastigotes (IC50s = 56.9 and 39.4 μM, respectively) with a cytotoxic concentration (CC50) value of greater than 1,000 μM in L929 cells[2]. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 22.5 mg/mL (101.18 mM) |
| 關(guān)鍵字 | unsaturated sesquiterpene alcohol | antioxidant | inhibit | anti-inflammatory | Inhibitor | α-BISABOLOL | oral | Levomenol | neuroprotective effects | Apoptosis | a-BISABOLOL | alpha-BISABOLOL |
| 相關(guān)庫 | 中藥單體化合物庫 | 經(jīng)典已知活性庫 | 風(fēng)味化合物庫 | 中藥抗炎分子庫 | 天然產(chǎn)物庫 | 神經(jīng)保護化合物庫 | 高通量篩選天然產(chǎn)物庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 藥食同源庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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