L-Thyroxine sodium NEW
Price | $47 |
Package | 500mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-13 |
Product Details
Product Name: L-Thyroxine sodium | CAS No.: 55-03-8 |
Purity: 99.56% | Supply Ability: 10g |
Release date: 2024/11/13 |
Product Introduction
Bioactivity
名稱 | L-Thyroxine sodium |
描述 | L-Thyroxine sodium (LT4 sodium), the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta. |
細胞實驗 | Cell lines: LS180V cells. Concentrations: 100 nM and 100μM. Incubation Time: 72 h. Method: LS180V cells are induced for 72 h with two l-T4 concentrations of 100 nM and 100 μM. |
動物實驗 | Animal Models: SD rats. Dosages: 20 μg/kg/day and 100 μg/kg/day. Administration: i.p. |
體外活性 | evothyroxine (L-T(4))can upregulate the expression of P-gp mRNA and protein in LS180 cells, but only L-T(4) and L-T(3) can produce the same effect in Caco-2 cells, which are relatively lacking in PXR[1] |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 27.5 mg/mL (34.38 mM) |
關鍵字 | T 4 | L-Thyroxine sodium | inhibit | L-Thyroxine | Levothyroxine | L Thyroxine sodium | T-4 | Thyroid Hormone Receptor | Inhibitor | THR | LThyroxine sodium |
相關產品 | Liothyronine | L-Thyroxine | 2,2-BIS(2-HYDROXY-5-BIPHENYLYL)PROPANE | Carbimazole | Liothyronine sodium | 2-Thiouracil |
相關庫 | 核受體化合物庫 | 經典已知活性庫 | 兒童藥物庫 | 藥物功能重定位化合物庫 | FDA 上市藥物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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