L-Lysine hydrochloride NEW
| Price | $5 | $0.2 |
| Package | 1KG | 1000KG |
| Min. Order: | 1KG |
| Supply Ability: | g-kg-tons, free sample is available |
| Update Time: | 2024-04-02 |
Product Details
| Product Name: L-Lysine hydrochloride | CAS No.: 657-27-2 |
| Min. Order: 1KG | Purity: 98% |
| Supply Ability: g-kg-tons, free sample is available | Release date: 2024/04/02 |
| Lead time: In stock, ready for shipment | Packaging: bag/bottle/drum/IBC |
| Delivery: By express, by air, by sea | Origin: Manufacturer, advantage product |
| COA, MSDS: Available, contact us for details | Name: Tina |
1. Materials information
| Name | L-lysine hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health. |
|---|---|
| Related Catalog | Signaling Pathways >> Others >> Others Research Areas >> Endocrinology Natural Products >> Others Research Areas >> Cardiovascular Disease Research Areas >> Inflammation/Immunology Research Areas >> Infection |
| In Vivo | L-lysine treatment attenuates pancreatic tissue injury induced by L-arginine by inhibiting the release of the inflammatory cytokine IL-6 and enhances antioxidant activity. Pre- or post-treatment with L-lysine leads to significant decreases in the levels of malondialdehyde and nitric oxide, while significant enhancement is observed in the activities of antioxidant enzymes (superoxide dismutase, catalase, and glutathione peroxidase) and glutathione[1]. L-lysine supplementation almost completely ameliorates vascular calcification. Dietary L-lysine strongly suppresses plasma intact parathyroid hormone in adenine rats and supports a proper bone-vascular axis. The conserved orientation of the femoral apatite in group Lys also evidences the bone-protective effects of L-lysine. Dietary L-lysine elevates plasma alanine, proline, arginine, and homoarginine but not lysine[2]. The dose-dependent delay in gastric emptying observed in rats is confirmed in humans with an increase in halftime of gastric emptying of 4 min/g L-lysine. Moreover, a dose-dependent increase in intestinal fluid accumulation is observed (0.4 mL/min/g L-lysine)[3]. |
| Animal Admin | Rats: Nephrocalcinosis in 6-week-old male Wistar rats is induced by continuous injection of rat PTH 1-34 at a dosage of 40 μg/kg per day via an osmotic mini-pump for 50 hours. L-lysine HCl or glycine at a dose of 20 mmol/kg is administered via a gastric tube at 2 hours, 14 hours, 26 hours, and 38 hours after the implantation of the osmotic pump. At the indicated periods, Serum and urinary biochemical parameters, urea nitrogen, albumin, calcium, inorganic phosphate, and magnesium are determined by clinical diagnostic reagents[2]. Mice: Four groups of mice (10 in each group) are assessed. Group I is the control. Animals in groups II-IV are injected intraperitoneally with L-arginine hydrochloride (400 mg/kg body weight [bw]) for 3 days. Group III animals are orally pre-treated with L-lysine(10 mg/kg bw), whereas group IV animals are orally post-treated with L-lysine(10 mg/kg bw). Serum samples are subjected to amylase, lipase, transaminase, and interleukin-6 (IL-6) assays. The pancreas is excised to measure the levels of malondialdehyde, nitric oxide, catalase, superoxide dismutase, reduced glutathione, and glutathione peroxidase[1]. |
| References | [1]. Al-Malki AL, et al. Suppression of acute pancreatitis by L-lysinein mice. BMC Complement Altern Med. 2015 Jun 23;15:193. [2]. Shimomura A, et al. Dietary L-lysineprevents arterial calcification in adenine-induced uremic rats. J Am Soc Nephrol. 2014 Sep;25(9):1954-65. [3]. Baruffol C, et al. L-lysine dose dependently delays gastric emptying and increases intestinal fluid volume in humans and rats. Neurogastroenterol Motil. 2014 Jul;26(7):999-1009. |
| Boiling Point | 311.5oC at 760 mmHg |
|---|---|
| Melting Point | 263 °C (dec.)(lit.) |
| Molecular Formula | C6H15ClN2O2 |
| Molecular Weight | 182.648 |
| Flash Point | 142.2oC |
| Exact Mass | 182.082199 |
| PSA | 89.34000 |
| LogP | 1.72990 |
| Water Solubility | 65 g/100 mL (20 oC) |
L-(+)-Lysine monohydrochloride MSDS(Chinese) |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Risk Phrases | R34 |
| Safety Phrases | S26-S36/37/39-S45-S24/25 |
| RIDADR | UN 1789 8/PG 3 |
| WGK Germany | 2 |
| RTECS | OL5650000 |
| HS Code | 29224100 |
 N-acetylcyclolysine CAS#:118477-18-2 ~99%  L-(+)-Lysine mo... CAS#:657-27-2 |
| Literature: Adamczeski,M.; Quinoa,E.; Crews,P. Journal of the American Chemical Society, 1989 , vol. 111, p. 647 |
 4-[(2R,5S)-2,5-... CAS#:129243-87-4 ~78%  H-D-Val-OH CAS#:640-68-6 L-(+)-Lysine mo... CAS#:657-27-2 |
| Literature: Raap, J.; Wielen, C. M. van der; Lugtenburg, J. Recueil des Travaux Chimiques des Pays-Bas, 1990 , vol. 109, # 4 p. 277 - 286 |
 Isobengamide E CAS#:118477-05-7 ~% L-(+)-Lysine mo... CAS#:657-27-2 |
| Literature: Journal of the American Chemical Society, , vol. 111, p. 647 |
| Precursor 4 | |
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| DownStream 9 | Previous 1/3 Next |
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CAS#:129243-83-0
CAS#:2280-44-6
CAS#:3105-95-1
CAS#:14905-30-7
CAS#:405-39-0
CAS#:462-94-2| HS Code | 2922499990 |
|---|---|
| Summary | HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |
2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
By Express
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
By Air
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
By Sea
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
For more details, pls contact us freely.
Email address: Tina@fdachem.com
Mob: 86 15225627621
WhatsApp/Skype/Wechat/LINE: 86 15225627621
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China
- Since: 2023-02-10
- Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro