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Postion:Product Catalog >KR-32568
KR-32568
  • KR-32568

KR-32568 NEW

Price $64 $155 $247
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-14

Product Details

Product Name: KR-32568 CAS No.: 852146-73-7
Purity: 99.89% Supply Ability: 10g
Release date: 2024/11/14

Product Introduction

Bioactivity

名稱KR-32568
描述KR-32568 is a sodium/hydrogen exchanger 1 (NHE-1) inhibitor (IC50: 230 nM) with potent cardioprotective effects. At a concentration of 10 μM, it restored cardiac systolic function in an isolated ischemic rat heart model. Additionally, KR-32568 (0.3 mg/kg) reduced myocardial infarction size in a rat model of ischemia and reperfusion injury.
體外活性KR-32568 (10 nM-1 μM) inhibited NHE-1-mediated platelet swelling induced by intracellular acidification in rabbit platelet-rich plasma in a concentration-dependent manner, with an IC50 value of 24 nM.[1]
體內(nèi)活性KR-32568 (0.1-1.0 mg/kg; i.v.; once) exerts effective cardioprotective effects in rats, such as reducing infarct size and significantly reducing the total number of premature ventricular contractions.[1]
存儲(chǔ)條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 90.0 mg/mL (344.5 mM), Sonication is recommended.
關(guān)鍵字KR-32568 | KR 32568 | KR32568
相關(guān)產(chǎn)品Phenytoin sodium | Lidocaine Hydrochloride hydrate | Lidocaine | Valproic Acid | Butamben | Lidocaine hydrochloride | L-Aspartic aicd sodium | Mebeverine hydrochloride | Amitriptyline hydrochloride | Riluzole | Benzocaine | Nefopam hydrochloride
相關(guān)庫疼痛相關(guān)化合物庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 神經(jīng)保護(hù)化合物庫 | 抑制劑庫 | 已知活性化合物庫 | 離子通道庫 | 抗癌化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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