KN-92 phosphate NEW
| Price | $64 | $107 | $178 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-04 |
Product Details
| Product Name: KN-92 phosphate | CAS No.: 1135280-28-2 |
| Purity: 99.31% | Supply Ability: 10g |
| Release date: 2024/11/04 |
Product Introduction
Bioactivity
| 名稱 | KN-92 phosphate |
| 描述 | KN-92 phosphate (KN92-H3PO4) is an inactive derivative of KN-93. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). |
| 體外活性 | KN-92 is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93. KN-93 inhibits histamine-induced aminopyrine uptake in parietal cells (IC50 = 300 nM). KN-93 has been used to implicate roles for CaMKII in Ca2+-induced Ca2+ release in cardiac myocytes, constitutive phosphorylation of 5-lipoxygenase in 3T3 cells, and Ca2+-dependent activation of HIF-1α in colon cancer cell. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 55 mg/mL (99.1 mM) |
| 關(guān)鍵字 | KN92 phosphate | derivative | inactive | KN 92 phosphate | KN 92 Phosphate | control | Inhibitor | KN-92 Phosphate | experimental | KN-92 | KN 92 | inhibit | KN92 | KN92 Phosphate | analog |
| 相關(guān)產(chǎn)品 | Phenoxybenzamine hydrochloride | Perphenazine | Dibucaine | Calmidazolium chloride | Promethazine | Tanshinone IIA sulfonate sodium | Melatonin | CaMKP Inhibitor | Cloxacepride | Nifedipine |
| 相關(guān)庫 | 表型篩選靶點(diǎn)鑒定庫 | 神經(jīng)退行性疾病化合物庫 | 經(jīng)典已知活性庫 | 神經(jīng)信號分子庫 | 激酶抑制劑庫 | 自噬庫 | 抑制劑庫 | NO PAINS 化合物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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