Ivermectin is a new kind of highly efficient semi-synthetic antibiotic insecticide, acaricide and nematocide, belonging to insect nerve agent and biopenetrant. The mechanism of action is to interfere with the neurophysiological activities of pests, stimulate the release of gamma-aminobutyric acid, act on nerve and muscle joints, increase the release of chloride ions, inhibit the information transmission of nerve joints, resulting in paralysis and death of pests and harmful mites. The product is colorless or light brownish yellow liquid. Ivermectin is a new type of broad-spectrum, high-efficiency, low-toxicity antibiotic antiparasitic drug, which has good repellant effect on both internal and external parasites, especially nematodes and arthropods. But not against tapeworms, flukes and protozoa. The antiparasitic effect of macrolides on nematodes and arthropods is to increase the release of the inhibitory transmitter gamma-aminobutyric acid (GABA) in worms, open the Cl ion channel controlled by glutamate, enhance the permeability of nerve membrane to Cl, thus blocking the transmission of nerve signals, and eventually paralyze the nerve, causing muscle cells to lose the ability to contract. Which causes the body to die.

Application:

1 It is effective in the treatment and control of penifilariasis, and the adverse reactions are lower than that of ethamine.

2 It is an antiparasitic agent with repellent activity against nematode, hookworm, roundworm, worm, insect and mite.