Iron saccharate NEW
Price | $8 |
Package | 25kg |
Min. Order: | 1kg |
Supply Ability: | 200000 |
Update Time: | 2024-10-25 |
Product Details
Product Name: Iron saccharate | CAS No.: 8047-67-4 |
EC-No.: 232-464-7 | Min. Order: 1kg |
Purity: 99% | Supply Ability: 200000 |
Release date: 2024/10/25 |
Iron sucrose is a complex of ferric hydroxide, Fe(OH)3, in sucrose, used intravenously to treat iron deficiency anemia in hemodialysis patients receiving supplemental therapy.
Iron sucrose is an intravenously administered iron product indicated in the treatment of iron deficiency anemia. It is frequently used in patients undergoing hemodialysis, those undergoing therapy, and/or patients who have chronic kidney disease. It is a type 2 complex which limits the maximum dose that can be given to 200mg which requires several administrations.
Iron sucrose is a form of the mineral iron. Iron is important for many functions in the body, especially for the transport of oxygen in the blood. Iron sucrose is used to treat iron deficiency anemia in people with kidney disease. It is usually given with another medication to promote the growth of red blood cells (such as Aranesp, Epogen, or Procrit). It is not for treating other forms of anemia not caused by iron deficiency.
Iron sucrose is a dark brown to reddish brown homogenous powder, almost odorless, sweet in taste and hygroscopic. Iron Sucrose Complex is a form of the mineral iron. Iron is important for many functions in the body, especially for the transport of oxygen in the blood. Iron sucrose injection is used to treat iron deficiency anemia in people with kidney disease. It is usually given with another medication to promote the growth of red blood cells (such as Aranesp, Epogen, or Procrit). This medication is not for treating other forms of anemia not caused by iron deficiency.
Name | Iron sucrose |
Synonyms | Saccharated iron oxide; Ferric hydroxide sucrose complex |
Molecular Formula | [Na2Fe5O8(H2O)]n.m(C12H22O11) |
CAS Registry Number | 8047-67-4 |
EINECS Number | 232-464-7 |
Powder:
Properties | |
Appearance | brown to dark brown powder |
Assay | Sucrose≥80.0% Fe 5.3%~6.0% |
PH | 10.5~11.1 |
Free Iron | 0.4% max |
Free Cl | 0.06% max |
Turbidity (pH) | 4.4-5.3 |
Specific gravity | 1.135 -1.165 |
Osmolarity | 1150-1350mOsmol/L |
Alkalinity | 0.5-0.8ml/ml |
Mw | 34000-60000 Da |
Mn | >24000 Da |
Mw/Mn | <1.7 |
Loss on dry | <0.5% |
Heavy Metal | <25 ppm |
Arsenic | <4ppm |
Transport and Package | |
Transport | Can ship as normal chemical |
Package | 25kg/Paper drum |
Liquid/Solution
TEST ITEM | SPECIFICATION |
Appearance | Brown - dark solution |
Identification A (Iron) | Conform to USP Iron test |
Identification B (Sucrose) | The retention time of the major peak in HPLC of the assay determination corresponds to that in the chromatogram of the standard determination under assay for sucrose |
Mw | 34000~60000 Da |
Mn | NLT 24,000 Da |
Mw/Mn | NMT 1.7 |
PH(2.0% w/v Fe) | 9.0-11.1 at 20 oC |
Turbidity (pH) | 4.4~5.3 |
Limit of Iron(II) | NMT 0.4% |
Specefic gravity | 1.135~1.165(20oC) |
Osmolarity | 1150~1350mOsmol/L |
Content of Chloride | NMT0.025%~0.055% |
The Ratio of Chloride and Iron | 7.0~14.0mg Cl/g Fe |
Assay-Sucrose | 45 %~65 % |
Assay-Iron | 3.5%~4.0% |
The Ratio of Sucrose and Iron | 13.0~17.0 |
Baterial endotoxin | NMT 3EU/mg Fe |
Total bacterial | NMT 100CFU/g |
Total mold/yeast | NMT 10CFU/g |
Function
Iron sucrose is an intravenous drug approved for treatment of iron deficiency anemia in adult patients suffering from kidney disease and being treated with hemodialysis or peritoneal dialysis and/or the hormone erythropietin. Dialysis is a procedure that takes over for the kidneys, filtering blood and removing waste. Erythropietin helps stimulate the production of red blood cells.
Ferric Carboxymaltose
Ferric Carboxymaltose is an iron replacement product and chemically, an iron carbohydrate complex. Ferric carboxymaltose is a iron replacement product indicated for the treatment of iron deficiency anemia in adult patients who have intolerance to oral iron or have had unsatisfactory response to oral iron or those who have non-dialysis dependent chronic kidney disease. Ferric carboxymaltose is a colloidal iron (III) hydroxide in complex with carboxymaltose, a carbohydrate polymer that release iron.
CAS NO.: 9007-72-1
Appearance: brown powder
Molecular structure:
Certificate of analysis
Item | Specification | Result |
Appearance | brown powder | complies |
Identification | Iron: positive | complies |
Dextrin: conforms | complies | |
Molecular weight | Mw 110,000~230,000Da | 141,610 |
Mn ≥60,000Da | 87,132 | |
Mw/Mn ≤1.9 | 1.6 | |
PH | 5.0~7.0 | 6.1 |
Limit of iron(II) | ≤1.2% | 0.2% |
Chloride content | ≤6.0% | 4.2% |
Residual solvents | Ethanol ≤5000ppm | 220ppm |
Loss on drying | ≤10.0% | 5.8% |
Copper | ≤320ppm | complies |
Assay of dextrin(on anhydrous basis) | 25~50% | 44.6% |
Assay of iron(on anhydrous basis) | 24~32% | 28.2% |
Hebei Jingbo New Material Technology Co., Ltd. was founded in 2007 , located in Shijiazhuang city which is the capital of Hebei Province and hub sector among Beijing Tianjin and Hebei and has advantage of convenient transportation . Our company is a modern high-tech chemical enterprise with Research & Development, production and sales.Our company has strong technical strength, advanced equipment, strict quality management system and high-quality after-sales service, adhers to the "customer first and forge ahead" business philosophy and insists on integrity as the company's survival.
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- Since: 2022-03-25
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