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Postion:Product Catalog >Biochemical Engineering>Saccharides>Disaccharides>Iron saccharate
Iron saccharate
  • Iron saccharate

Iron saccharate NEW

Price $8
Package 25kg
Min. Order: 1kg
Supply Ability: 200000
Update Time: 2024-10-25

Product Details

Product Name: Iron saccharate CAS No.: 8047-67-4
EC-No.: 232-464-7 Min. Order: 1kg
Purity: 99% Supply Ability: 200000
Release date: 2024/10/25

Iron sucrose is a complex of ferric hydroxide, Fe(OH)3, in sucrose, used intravenously to treat iron deficiency anemia in hemodialysis patients receiving supplemental therapy.

Iron sucrose is an intravenously administered iron product indicated in the treatment of iron deficiency anemia. It is frequently used in patients undergoing hemodialysis, those undergoing therapy, and/or patients who have chronic kidney disease. It is a type 2 complex which limits the maximum dose that can be given to 200mg which requires several administrations.

Iron sucrose is a form of the mineral iron. Iron is important for many functions in the body, especially for the transport of oxygen in the blood. Iron sucrose is used to treat iron deficiency anemia in people with kidney disease. It is usually given with another medication to promote the growth of red blood cells (such as Aranesp, Epogen, or Procrit). It is not for treating other forms of anemia not caused by iron deficiency.

Iron sucrose is a dark brown to reddish brown homogenous powder, almost odorless, sweet in taste and hygroscopic. Iron Sucrose Complex is a form of the mineral iron. Iron is important for many functions in the body, especially for the transport of oxygen in the blood. Iron sucrose injection is used to treat iron deficiency anemia in people with kidney disease. It is usually given with another medication to promote the growth of red blood cells (such as Aranesp, Epogen, or Procrit). This medication is not for treating other forms of anemia not caused by iron deficiency.

 

NameIron sucrose
SynonymsSaccharated iron oxide; Ferric hydroxide sucrose complex
Molecular Formula[Na2Fe5O8(H2O)]n.m(C12H22O11)
CAS Registry Number8047-67-4
EINECS  Number232-464-7

Powder:


Properties
Appearancebrown to dark brown powder
AssaySucrose≥80.0%
Fe 5.3%~6.0%
PH10.5~11.1
Free Iron0.4% max
Free Cl0.06% max
Turbidity (pH)4.4-5.3
Specific gravity1.135 -1.165
Osmolarity1150-1350mOsmol/L
Alkalinity0.5-0.8ml/ml
Mw34000-60000 Da
Mn>24000 Da
Mw/Mn<1.7
Loss on dry<0.5%
Heavy Metal<25 ppm
Arsenic<4ppm
Transport and Package
TransportCan ship as normal chemical
Package25kg/Paper drum


Liquid/Solution


TEST ITEMSPECIFICATION
AppearanceBrown - dark  solution
Identification A (Iron)Conform to USP Iron test
Identification B (Sucrose)The retention time of the major peak in HPLC of the assay determination corresponds to that in the chromatogram of the standard determination under assay for sucrose
Mw34000~60000 Da
MnNLT  24,000 Da
Mw/MnNMT 1.7
PH(2.0% w/v Fe)9.0-11.1 at  20 oC
Turbidity (pH)4.4~5.3
Limit of Iron(II)NMT 0.4%
Specefic gravity1.135~1.165(20oC)
Osmolarity1150~1350mOsmol/L
Content of ChlorideNMT0.025%~0.055%
The Ratio of Chloride and Iron7.0~14.0mg Cl/g Fe
Assay-Sucrose45 %~65 %
Assay-Iron3.5%~4.0%
The Ratio of Sucrose and Iron13.0~17.0
Baterial endotoxinNMT 3EU/mg Fe
Total bacterialNMT 100CFU/g
Total mold/yeastNMT 10CFU/g


Function
Iron sucrose is an intravenous drug approved for treatment of iron deficiency anemia in adult patients suffering from kidney disease and being treated with hemodialysis or peritoneal dialysis and/or the hormone erythropietin. Dialysis is a procedure that takes over for the kidneys, filtering blood and removing waste. Erythropietin helps stimulate the production of red blood cells.


Ferric Carboxymaltose


Ferric Carboxymaltose is an iron replacement product and chemically, an iron carbohydrate complex. Ferric carboxymaltose is a iron replacement product indicated for the treatment of iron deficiency anemia in adult patients who have intolerance to oral iron or have had unsatisfactory response to oral iron or those who have non-dialysis dependent chronic kidney disease. Ferric carboxymaltose is a colloidal iron (III) hydroxide in complex with carboxymaltose, a carbohydrate polymer that release iron.
CAS NO.: 9007-72-1
Appearance: brown powder
Molecular structure:


Certificate of analysis


Item

Specification

Result

Appearance

brown powder

complies

Identification

Iron: positive

complies


Dextrin: conforms

complies

Molecular weight

Mw 110,000~230,000Da

141,610


Mn ≥60,000Da

87,132


Mw/Mn  ≤1.9

1.6

PH

5.0~7.0

6.1

Limit of iron(II)

≤1.2%

0.2%

Chloride content

≤6.0%

4.2%

Residual solvents

Ethanol  ≤5000ppm

220ppm

Loss on drying

≤10.0%

5.8%

Copper

≤320ppm

complies

Assay of dextrin(on anhydrous basis)

25~50%

44.6%

Assay of iron(on anhydrous basis)

24~32%

28.2%


Hebei Jingbo New Material Technology Co., Ltd. was founded in 2007 , located in Shijiazhuang city which is the capital of Hebei Province and hub sector among Beijing Tianjin and Hebei and has advantage of convenient transportation . Our company is a modern high-tech chemical enterprise with Research & Development, production and sales.Our company has strong technical strength, advanced equipment, strict quality management system and high-quality after-sales service, adhers to the "customer first and forge ahead" business philosophy and insists on integrity as the company's survival.

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