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Postion:Product Catalog >IP7e
IP7e
  • IP7e

IP7e NEW

Price $117 $289 $455
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: IP7e CAS No.: 500164-74-9
Purity: 98.54% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameIP7e
DescriptionIP7e (isoxazolo-pyridinone 7e) is a Nurr1 activator with an EC50 value of 3.9 nM.
In vivoIP7e(10 mg/kg) attenuates inflammation and neurodegeneration in spinal cords of EAE mice by an NF-kB pathway-dependent process. IP7e preventive treatment reduces the incidence and the severity of an MS murine model, i.e. experimental autoimmune encephalomyelitis (EAE)[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 95 mg/mL (243.32 mM), Sonication is recommended.
Keywordsorally | Nurr1 | NF-kB | IP7e | Inhibitor | inhibit | brain-penetrant
Related Compound LibrariesNuclear Receptor Compound Library | Bioactive Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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