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Inarigivir ammonium NEW
Price | $328 | $689 | $1050 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: Inarigivir ammonium | CAS No.: 2172788-92-8 |
Purity: 99.13% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | Inarigivir ammonium |
Description | Inarigivir ammonium (SB-9200 ammonium) is a dinucleotide antiviral compound that significantly reduces HBV DNA in transgenic mice expressing hepatitis B virus. Inarigivir is an agonist of retinoic acid-inducible gene-I (RIG-I) that activates intracellular innate immunity. |
In vitro | Inarigivir exhibits activity against HBV (hepatitis B virus) variants, including those resistant to all approved nucleo(s)tide analogues for chronic hepatitis B treatment[1]. |
In vivo | Administration of 100 mg/kg/day Inarigivir (ip) significantly reduces viral DNA in the liver and shows anti-HBV activity while serum HBV DNA is not reduced. Inarigivir does not affect levels of HBV RNA in liver, levels of HBeAg in serum, or mean titers of HBsAg. The minimal effective dose is identified to be between 1.6 and 0.5 mg/kg/day using liver HBV DNA values[2]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 98 mg/mL (162.11 mM) |
Keywords | SB-9000 | HBV | ORI9020 | HCV | Hepatitis B virus | ORI 9020 | antiviral | inhibit | Inarigivir | Inhibitor | ORI-9020 | RIG-I | SB9000 | SB 9000 | Huh7 | Inarigivir ammonium |
Inhibitors Related | Osthole | Tenofovir Disoproxil Fumarate | 4-Hydroxyacetophenone | Tenofovir |
Related Compound Libraries | Bioactive Compound Library | Anti-Viral Compound Library | Orally Active Compound Library | Bioactive Compounds Library Max | Anti-Infection Compound Library | Nucleotide Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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