Product Details
Product Name:
Idactamab |
CAS No.:
2245205-37-0 |
Purity:
> 95% |
Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
Name | Idactamab |
Description | Idactamab (INT-001) is a monoclonal antibody to the human amino acid transport protein ASCT2. |
In vitro | Idactamab exhibits inhibitory effects on various hematologic cancer cell lines, with an IC50 ranging from 0.05 to 65 ng/mL [2].
ASCT2 (SLC1A5) is a multi-channel, Na+-dependent neutral amino acid transporter that mediates the uptake of amino acids required for tumor growth and progression [2]. |
In vivo | Idactamab enhances the survival rates of three disseminated acute myeloid leukemia (AML) cell line models: TF1α (high expression of ASCT2), MOLM-13 (low expression of ASCT2), and M.V.411 (high expression of ASCT2). The corresponding minimum inhibitory concentrations are 0.05 mg/kg, 0.1 mg/kg, and 0.1 mg/kg, respectively [1]. |
Storage | store at low temperature | store at -80°C | Shipping with blue ice. |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |