Hydroxocobalamin Chloride NEW
Price | Get Latest Price |
Package | 10G |
Min. Order: | 1G |
Supply Ability: | 100kg |
Update Time: | 2024-04-08 |
Product Details
Product Name: Hydroxocobalamin Chloride | CAS No.: 58288-50-9 |
EC-No.: 261-200-3 | Min. Order: 1G |
Purity: 99% | Supply Ability: 100kg |
Release date: 2024/04/08 |
Manufacturer Provide Vitamin B12 Hydroxycobalamin HCl CAS 58288-50-9 Hydroxocobalamin Chloride
Introduction
Name: Hydroxocobalamin Chloride
C.A.S NO. : 58288-50-9
Chemical name: Vitamin B12 Hydroxycobalamin HCl
Assay (%)(HPLC, Basis on drying):99%
Molecular formula: C62H89ClCoN13O15P
Appearance: Dark Red Crystals or Crystalline Powder
Storage Condition: Store in cool and dry places ,keep away from strong light
Hydroxocobalamin, also known as hydroxycobalamin, is a member of the class of compounds known as cobalamin derivatives. These organic compounds contain a corrin ring, a cobaltatom, and a nucleotide moiety. Cobalamin derivatives are actually derived from vitamin B12. Hydroxocobalamin is practically insoluble (in water) and a moderately acidic compound (based on its pKa). Hydroxocobalamin is formally rated as a possibly carcinogenic (IARC 2B) potentially toxic compound. Hydroxocobalamin is a drug used in the treatment of pernicious anemia and in the prevention and treatment of vitamin B12 deficiency arising from alcoholism, malabsorption, tapeworm infestation, celiac disease, hyperthyroidism, hepatic-biliary tract disease, persistent diarrhea, ileal resection, pancreatic cancer, renal disease, prolonged stress, vegan diets, macrobiotic diets, and other restrictive diets. Hydroxocobalamin is also used in the treatment of known or suspected cyanide poisoning.
Use
1) Hydroxocobalamin is commonly used to address vitamin B-12 deficiency.
2) Hydroxocobalamin received approval for use as a treatment for cyanide poisoning.
3) Hydroxocobalamin has been identified as a scavenger of nitric oxide, an essential muscle regulator that also acts as a free radical.
Item | Specification | Test Results | Testing methods |
Appearance | Dark red, crystals or crystalline powder | Complies | Monograph:0547 Visual method |
Identifiction A | UV:Absorption maxima at 274±1nm,351±1nm and 525±2nm.274±1nm,351±1nm,525±2nm | Complies | Ph.Eur.monograph Ph.Eur. <2.2.25> |
A274nm/A351nm: 0.75~0.83 A525nm/A351nm: 0.31~0.35 | 0.79 0.33 | ||
Identifiction B | TLC:The principal spot in the chromatogram obtained with the test solution is similar in position,colour and size to the principal spot in the chromatogram obtained with the reference solution | Complies | Ph.Eur.monograph Ph.Eur. <2.2.27> |
Identifiction C | Chlorides:It gives reaction(a) of chlorides | Complies | Ph.Eur.monograph<2.3.1>Chlorides |
Loss on drying | 8.0%~12.0% | 8.4% | Ph.Eur.monograph Ph.Eur<2.2.32> |
Assay | 96.0%~102.0% | 98.8% | Ph.Eur.monograph Ph.Eur<2.2.25> |
Related substances | ≤5% | 2% | Ph.Eur.monograph/ Ph.Eur<2.2.29>(HPLC) |
Acetone | ≤5000ppm | 22ppm | In house/(GC) (GC)SOP-QC-158-04-03 |
Total aerobic microbial count | ≤1000cfu/g | <10cfu/g | ChP 2015<1105> |
The total combined yeasts/mould count | ≤100cfu/g | <10cfu/g |
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