Product Details
Product Name:
HNHA |
CAS No.:
926908-04-5 |
Purity:
98.04% |
Supply Ability:
10g |
Release date:
2024/11/18 |
Product Introduction
Bioactivity
名稱 | HNHA |
描述 | HNHA is an inhibitor of HDAC. |
體外活性 | Treatment of cells with HNHA could elicite histone hyperacetylation resulting in an up-regulation of cell cycle arrest, p21 transcription, and an inhibition of HT1080 cell invasion. HNHA was able to inhibit in-vitro HDAC enzyme activity as well as proliferation of human fibrosarcoma cells (HT1080). |
體內(nèi)活性 | Several HDAC inhibitors, including MS-27-275 and a hydroxyamide-based HDAC inhibitors such as SAHA have been investigated extensively and shown to inhibit tumor growth in vivo. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | Ethanol : 15 mg/mL (49.44 mM) DMSO : 15 mg/mL (49.44 mM)
|
關(guān)鍵字 | Histone deacetylases | HIF/HIF Prolyl-Hydroxylase | inhibit | Inhibitor | HIF-PH | HIFs | FM3A cells | MCF-7 cells | Anti-cancer activity | Matrix metalloproteinases | Breast cancer | HNHA | Hypoxia-inducible factors | MMP | HDAC |
相關(guān)產(chǎn)品 | Sodium 4-phenylbutyrate | Curcumin |
相關(guān)庫 | 組蛋白修飾化合物庫 | 經(jīng)典已知活性庫 | 表觀遺傳庫 | 抑制劑庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 抗癌化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |