HG106 NEW

Price	$58	$147	$239
Package	1mg	5mg	10mg

Min. Order:
Supply Ability:	10g
Update Time:	2024-11-19

Product Details

Product Name: HG106	CAS No.: 928712-10-1
Purity: 99.62%	Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

Name	HG106
Description	HG106, which is anti-inflammatory and may be used to treat the growth of diseases such as malignant tumours caused by mutations in the RAS gene., which is anti-inflammatory and may be used to treat the growth of diseases such as malignant tumours caused by mutations in the RAS gene.
In vitro	We identified a potent SLC7A11 inhibitor, HG106, that markedly decreased cystine uptake and intracellular glutathione biosynthesis. Furthermore, HG106 exhibited selective cytotoxicity toward KRAS-mutant cells by increasing oxidative stress- and ER stress-mediated cell apoptosis. [1]
In vivo	Treatment of KRAS-mutant LUAD with HG106 in several preclinical lung cancer mouse models led to marked tumor suppression and prolonged survival. [1]
Storage	store at low temperature \| Shipping with blue ice.
Solubility Information	H2O : Insoluble Ethanol : Insoluble DMSO : 18.9 mg/mL (59.7 mM)
Keywords	Acetamide,2chloroN[2(4methoxyphenyl)2Hbenzotriazol5yl] \| HG-106 \| HG 106 \| HG106
Related Compound Libraries	Bioactive Compound Library \| Anti-Aging Compound Library \| Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.