GW9508 NEW
| Price | $29 | $48 | $78 |
| Package | 10mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-14 |
Product Details
| Product Name: GW9508 | CAS No.: 885101-89-3 |
| Purity: 99.19% | Supply Ability: 10g |
| Release date: 2024/11/14 |
Product Introduction
Bioactivity
| 名稱 | GW9508 |
| 描述 | GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner. |
| 體內(nèi)活性 | In MIN6 cells, GW9508 stimulates insulin secretion in a dose-dependent manner and enhances insulin secretion mediated by KCl. In rat β-cells, GW9508 induces hyperpolarization and the opening of KATP channels. In HaCaT cells, GW9508 inhibits the expression of IL-11, IL-24, and IL-33 induced by TNF-α and IFN-γ. Additionally, in normal human epidermal keratinocytes, GW9508 suppresses the production of CCL5 and CXCL10. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | Ethanol : 34.7 mg/mL (100 mM) DMSO : 40 mg/mL (115.14 mM), Sonication is recommended. |
| 關(guān)鍵字 | TNF-α | KcsA | insulin | GPR40 | glucose-sensitive | Potassium Channel | GPR120 | Free Fatty Acid Receptor | KATP | FFA1 | anti-inflammatory | CCL5 | CXCL10 | GW9508 | Inhibitor | inhibit | GW-9508 | IFN-γ | FFAR | anti-atherosclerotic |
| 相關(guān)產(chǎn)品 | Minoxidil sulfate | Quinine | Monomethyl fumarate | (±)-Naringenin | Tolbutamide | Tetraethylammonium bromide | Halothane | Butamben | Benzyl nicotinate | Cloperastine hydrochloride | 2,2,2-Trichloroethanol | Indapamide |
| 相關(guān)庫 | 表型篩選靶點鑒定庫 | 經(jīng)典已知活性庫 | 疼痛相關(guān)化合物庫 | 膜蛋白靶向化合物庫 | 神經(jīng)保護化合物庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 活性脂質(zhì)化合物庫 | GPCR靶點分子庫 | 離子通道庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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