
GW9508 NEW
Price | $29 | $48 | $78 |
Package | 10mg | 25mg | 50mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-04-29 |
Product Details
Product Name: GW9508 | CAS No.: 885101-89-3 |
Purity: 98.31% | Supply Ability: 10g |
Release date: 2025/04/29 |
Product Introduction
Bioactivity
Name | GW9508 |
Description | GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner. |
In vivo | In MIN6 cells, GW9508 stimulates insulin secretion in a dose-dependent manner and enhances insulin secretion mediated by KCl. In rat β-cells, GW9508 induces hyperpolarization and the opening of KATP channels. In HaCaT cells, GW9508 inhibits the expression of IL-11, IL-24, and IL-33 induced by TNF-α and IFN-γ. Additionally, in normal human epidermal keratinocytes, GW9508 suppresses the production of CCL5 and CXCL10. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | Ethanol : 34.7 mg/mL (99.88 mM), Sonication is recommended. DMSO : 150 mg/mL (431.77 mM), Sonication is recommended. |
Keywords | TNF-α | PotassiumChannel | Potassium Channel | KcsA | KATP | insulin | Inhibitor | inhibit | IFN-γ | GW-9508 | GW9508 | GPR40(FFA1) | GPR40 | GPR120 | glucose-sensitive | Free Fatty Acid Receptor | FFAR | FFA1 | CXCL10 | CCL5 | anti-inflammatory | anti-atherosclerotic |
Inhibitors Related | Minoxidil sulfate | Tannic acid | Monomethyl fumarate | Hydrochlorothiazide | Tetraethylammonium bromide | Azathioprine | Halothane | Ursodeoxycholic acid | Benzyl nicotinate | Cloperastine hydrochloride | Nifedipine | Indapamide |
Related Compound Libraries | Pain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Neuroprotective Compound Library | Endocrinology-Hormone Compound Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Bioactive Lipid Compound Library | Potassium Channel Targeted Library | Ion Channel Targeted Library | GPCR Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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