
GSK369796 Dihydrochloride NEW
Price | $72 | $152 | $205 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-04-28 |
Product Details
Product Name: GSK369796 Dihydrochloride | CAS No.: 1010411-21-8 |
Purity: 100% | Supply Ability: 10g |
Release date: 2025/04/28 |
Product Introduction
Bioactivity
Name | GSK369796 Dihydrochloride |
Description | GSK369796 Dihydrochloride (N-tert-butylisoquine),is an anti-malaria drug candidate. is an affordable and effective antimalarial and inhibits hERG potassium ion channel repolarization(IC50 of 7.5 μM) |
In vitro | Analysis of antiviral activities indicated that GSK369796 has high anti-DENV activity in the DENV2 replicon expressing cells with EC50 values of 5.06 ± 0.86 μM. The infectivity assays revealed the EC50 values of 3.03 ± 0.35 μM. The mode of action of this compound is through inhibition of autophagy, thereby affecting DENV2 replication. Moreover, this compounds also showed antiviral activity against the rapidly emerging Zika virus (ZIKV) with EC50 values of 2.57 ± 0.09 μM (GSK369796)[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 75 mg/mL (174.91 mM), Sonication is recommended. |
Keywords | PotassiumChannel | potassium ion channel | Potassium Channel | Parasite | KcsA | Inhibitor | inhibit | GSK-369796 Dihydrochloride | GSK369796 Dihydrochloride | GSK-369796 | GSK369796 | GSK 369796 Dihydrochloride | GSK 369796 |
Inhibitors Related | Kaempferol | Kojic acid | Tannic acid | Urethane | Hydroxychloroquine | Metronidazole | Nitazoxanide | Doxycycline | Chloroquine phosphate | Diethyltoluamide | Artemisinin | DL-Methionine |
Related Compound Libraries | Anti-Parasitic Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | ReFRAME Related Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Cancer Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
Product name | Price | Suppliers | Update time | |
---|---|---|---|---|
$180.00/1kg |
Hebei Zhuanglai Chemical Trading Co.,Ltd
|
2024-06-03 | ||
$339.00/1kg |
VIP5Y
|
Shanghai UCHEM Inc.
|
2023-11-16 | |
$1.00/1kg |
VIP5Y
|
RongNa Biotechnology Co.,Ltd
|
2024-03-26 |
- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
INQUIRY