Product Details
Product Name:
GSK2795039 |
CAS No.:
1415925-18-6 |
Purity:
98.68% |
Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
Name | GSK2795039 |
Description | GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2 (NOX2) (pIC50: 6 in different cell-free assays). |
In vitro | GSK2795039 (25 μM; 24 hours) mitigates FeSO4 and LPS-induced apoptosis and reduces caspase-3-positive PC12 cells[2]. |
In vivo | GSK2795039 (intraperitoneal injection; 100 mg/kg; 1 hour prior) reduces activity in a murine acute pancreatitis model and decreases serum amylase levels induced by systemic cerulein injection[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 40 mg/mL (88.78 mM), Sonication is recommended.
|
Keywords | Inhibitor | Reactive Oxygen Species | NADPH Oxidase | NOX | inhibit | GSK2795039 | Apoptosis | GSK-2795039 | GSK 2795039 |
Inhibitors Related | Stavudine | 5-Fluorouracil | Imeglimin hydrochloride | Acetylcysteine | Myricetin | Sodium 4-phenylbutyrate | L-Ascorbic acid | Dextran sulfate sodium salt (MW 4500-5500) | Metronidazole | Sorafenib | Tributyrin | Glucosamine |
Related Compound Libraries | Cuproptosis Compound Library | Ferroptosis Compound Library | Bioactive Compound Library | Anti-Breast Cancer Compound Library | Anti-Obesity Compound Library | Inhibitor Library | Anti-Prostate Cancer Compound Library | Mitochondria-Targeted Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |