GS-829845 NEW
| Price | $39 | $57 | $90 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-11 |
Product Details
| Product Name: GS-829845 | CAS No.: 1257705-09-1 |
| Purity: 99.78% | Supply Ability: 10g |
| Release date: 2024/11/11 |
Product Introduction
Bioactivity
| 名稱 | GS-829845 |
| 描述 | GS-829845 is a JAK1 inhibitor, the main component of the active metabolite of Filgotinib, which is approximately 10-fold less potent and has a longer half-life than the parent. |
| 體內(nèi)活性 | Filgotinib did not alter metformin exposures, indicating that filgotinib and GS-829845 do not inhibit OCT2 and MATE1/2K at the clinical doses. Filgotinib was generally well-tolerated when administered alone or with the co-administered drugs in the studies. Results from these studies were the basis to enable the use of P-gp modulators and substrates of OCT2, MATE1, and MATE2K with filgotinib without the need for dose modifications in the current approved rheumatoid arthritis population.[2] |
| 存儲(chǔ)條件 | Shipping with blue ice. |
| 溶解度 | DMSO : 90.0 mg/mL (251.8 mM), Sonication is recommended. |
| 關(guān)鍵字 | GS 829845 | GS829845 | GS-829845 |
| 相關(guān)產(chǎn)品 | Delgocitinib | Clofibric acid | Mycophenolate Mofetil | CLOZAPINE N-OXIDE | Monomethyl fumarate | Ruxolitinib | Tofacitinib Citrate | Isonicotinic acid | Ruxolitinib phosphate | Ampyrone | 4-Methylamino antipyrine | Nicotinamide N-oxide |
| 相關(guān)庫(kù) | 經(jīng)典已知活性庫(kù) | 激酶抑制劑庫(kù) | 抑制劑庫(kù) | 已知活性化合物庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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