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Postion:Product Catalog >GNF-6231
GNF-6231
  • GNF-6231

GNF-6231 NEW

Price $43 $67 $117
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-15

Product Details

Product Name: GNF-6231 CAS No.: 1243245-18-2
Purity: 99.54% Supply Ability: 10g
Release date: 2024/11/15

Product Introduction

Bioactivity

名稱(chēng)GNF-6231
描述GNF-6231 is a potent, selective, and orally bioavailable Porcupine inhibitor that blocks Wnt signaling.
體外活性GNF-6231 shows IC50s of greater than 10 μM on all CYP isoforms tested[1].
體內(nèi)活性GNF-6231 has favorable potency and a PK profile across preclinical species upon oral administration.?The reference for orally in MMTV-Wnt1 tumor-bearing mice is dosed at 3 mg/kg.?GNF-6231 showed very robust dose-related antitumor efficacy[1].
存儲(chǔ)條件store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 36 mg/mL (80.3 mM)
關(guān)鍵字GNF-6231 | GNF6231 | GNF 6231
相關(guān)產(chǎn)品LGK974 | IWP L6 | Porcn-IN-1 | ETC-159 | WHN-88 | IWP-2 | Wnt-C59 | IWP-O1
相關(guān)庫(kù)高選擇性抑制劑庫(kù) | 經(jīng)典已知活性庫(kù) | 血液病分子庫(kù) | 抑制劑庫(kù) | 干細(xì)胞分化化合物庫(kù) | 口服活性化合物庫(kù) | 已知活性化合物庫(kù) | 含氟化合物庫(kù)

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Recommended supplier

Product name Price   Suppliers Update time
$2500.00/100mg
VIP1Y
TargetMol Chemicals Inc.
2024-10-28
$46.00/1mg
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2024-11-13
$5.00/5KG
VIP7Y
Career Henan Chemical Co
2019-09-03
$117.00/25mg
VIP3Y
TargetMol Chemicals Inc.
2024-11-15
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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