Glucoraphanin NEW
| Price | $48 | $117 | $195 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Glucoraphanin | CAS No.: 21414-41-5 |
| Purity: 98.86% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Glucoraphanin |
| Description | Glucoraphanin, the precursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, has antioxidant activity. |
| Animal Research | Male C57BL/6JSlc mice are 7 weeks of age. The Nrf2 knockout (Nrf2?/?) mouse strain is used in the assay. After 1 week of acclimation, mice are fed normal chow (NC) (containing 2.2% dextrinized cornstarch, 10% kcal from fat), NC containing 0.3% glucoraphanin (NC-GR) (containing 2.2% extract powder), an HFD (containing 2.2% dextrinized cornstarch, 60% kcal from fat), or an HFD containing 0.3% glucoraphanin (HFD-GR) (containing 2.2% extract powder) for 14 weeks. Both the NC and the HFD containing cornstarch or glucoraphanin are prepared. All mice studied are maintained on a 12-h light/dark cycle at 24-26°C with free access to water and food [1]. |
| In vivo | Glucoraphanin reduces weight gain, enhances energy expenditure, improves insulin sensitivity, and glucose tolerance in HFD-fed mice, but it does not exert these effects in Nrf2-/-. It blocks HFD-induced reduction of Ucp1 protein levels in white adipose depots of wild-type mice but not in Nrf2-/-, alleviates HFD-induced hepatic steatosis and oxidative stress, and suppresses HFD-induced proinflammatory activation of macrophages in the liver and adipose tissue [1]. Additionally, pellets containing 0.1% Glucoraphanin (GF) significantly attenuate decreased social avoidance time and sucrose preference in stressed mice [2]. |
| Storage | store at low temperature,store under nitrogen,keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : 74 mg/mL (169.14 mM) |
| Keywords | Reactive Oxygen Species | Inhibitor | Glucoraphanin | inhibit |
| Inhibitors Related | Sodium Thiocyanate | Imeglimin hydrochloride | L-Ascorbic acid | α-Vitamin E | Propyl gallate | L-Tartaric acid | Glucosamine | Neohesperidin | D-(+)-Glucono-1,5-lactone | L-Cystine | Lycopene | Naringenin |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Selected Plant-Sourced Compound Library | Natural Product Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Anti-Aging Compound Library | Ancient Chinese Classical Formulas Compound Library | Food as Medicine Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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