Glaucocalyxin A NEW
| Price | $100 |
| Package | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-16 |
Product Details
| Product Name: Glaucocalyxin A | CAS No.: 79498-31-0 |
| Purity: 99.56% | Supply Ability: 10g |
| Release date: 2024/11/16 |
Product Introduction
Bioactivity
| 名稱 | Glaucocalyxin A |
| 描述 | 1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expression of X-linked inhibitor of apoptosis protein. 3. Glaucocalyxin A inhibits Akt phosphorylation, suppresses proliferation, and promotes apoptosis in a dose-dependent manner, but not in normal glial cells. 4. Glaucocalyxin A inhibits collagen-stimulated tyrosine phosphorylation of Syk, LAT, and phospholipase Cγ2, the signaling events in collagen receptor GPⅥ pathway. 5. Glaucocalyxin A could potentially be developed as an antiplatelet and antithrombotic agent, can inhibit platelet p-selectin secretion and integrin activation by convulxin, is a GPVI selective ligand. |
| 存儲條件 | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc. : Soluble DMSO : 6.88 mg/mL (20.68 mM), Sonication is recommended. |
| 關(guān)鍵字 | Phosphoinositide 3-kinase | inhibit | Apoptosis | Protein kinase B | Glaucocalyxin A | PI3K | Akt | Inhibitor | PKB |
| 相關(guān)產(chǎn)品 | Stavudine | TBHQ | 5-Fluorouracil | Meclizine dihydrochloride | Dextran sulfate sodium salt (MW 4500-5500) | Sodium 4-phenylbutyrate | Sorafenib | Tributyrin | Lidocaine hydrochloride | 2,3-Butanediol | Alginic acid | Oleic acid |
| 相關(guān)庫 | 抗癌天然產(chǎn)物庫 | 萜類天然產(chǎn)物庫 | 經(jīng)典已知活性庫 | 神經(jīng)退行性疾病化合物庫 | 激酶抑制劑庫 | 天然產(chǎn)物庫 | 抑制劑庫 | 高通量篩選天然產(chǎn)物庫 | 已知活性化合物庫 | 抗癌活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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