Glabridin is a natural whitening agent isolated from glycyrrhizin, glycyrrhizin is extracted from the roots of specific varieties of glycyrrhizin plants (such as uralglycyrrhizin, glycyrrhizin, glycyrrhizin, etc.), all natural, pollution-free, without any side effects on the human body. At room temperature, it is a red-brown powder, insoluble in water, easily soluble in organic solvents, such as ethanol, propylene glycol, 1, 3-butanediol, etc. Licorice is a perennial herb that grows in southern Europe, Asia and the Mediterranean, and is widely cultivated in Russia, Spain, Iran and India. Glabridin can reduce phlegm, emollient skin, anti-inflammatory, anti-filtration pathogens, anti-liver toxins and antibacterial. Because of these properties, licorice has been extensively studied in medicine and food. Glabridin can be used in cosmetics, it has whitening, anti-inflammatory, antibacterial and antioxidant effects, is a very valuable cosmetic raw material. Light glycyrrhiza, because of its efficient ability to inhibit reactive oxygen species and melanin, is known as "whitening gold", one is the praise of whitening efficacy, the second is the light glycyrrhiza single gram price is equivalent to gold, only a few brands dare to use it as a whitening ingredient.

Efficacy and effect

Glabridin has strong antibacterial effects, preventing inflammation caused by ultraviolet light, pigmentation and rough skin, can clear superoxide ions, inhibit hemolysis caused by hydrogen peroxide, inhibit tyrosinase activity, and inhibit dopa pigment tautometry and DHICA oxidase activity. It is a fast, efficient, green cosmetic additive for whitening and freckle removal. It has the ability to remove oxygen free radicals similar to SOD (peroxide dismutase), but also has the antioxidant free radical ability similar to vitamin E. In addition, glycyrrhizin also has a strong oxidation, anti-atherosclerosis and a certain degree of blood lipid, blood pressure lowering effect.

Pharmacological action

Glabridin is one of the main flavonoids in glycyrrhizin. It shows a strong anti-free radical oxidation effect in the cytochrome P450/NADPH oxidation system, and can significantly inhibit free radicals generated during metabolism in the body, so as to avoid the damage of biological macromolecules (low-density lipoprotein LDL,DNA) and cell walls that are sensitive to oxidation by free radicals. Thus, some pathological changes related to free radical oxidation can be prevented, such as atherosclerosis, cell senescence and so on. In addition, glycyrrhizin has certain effects on lowering blood lipids and blood pressure.