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Postion:Product Catalog >Organic Chemistry>Organic fluorine compound>Fluorine propane series>GI-530159
GI-530159
  • GI-530159

GI-530159 NEW

Price $111 $1
Package 1KG 1000KG
Min. Order: 1KG
Supply Ability: g-kg-tons, free sample is available
Update Time: 2024-01-08

Product Details

Product Name: GI-530159 CAS No.: 69563-88-8
Min. Order: 1KG Purity: 99%
Supply Ability: g-kg-tons, free sample is available Release date: 2024/01/08
Lead time: In stock Packaging: bag/bottle/drum
Delivery: express Origin: Manufacturer

1. Materials information

Use of GI-530159


GI-530159 is a selective, mechanosensitive opener of TREK1 (K2P2.1) and TREK2 (K2P10.1) channels, with an EC50 of 0.76 μM for TREK1. GI-530159 displays selectivity for TREK1/2 over TRAAK, TASK3 and other potassium channels. GI-530159 reduces rat dorsal root ganglion neuron excitability[1].

Name2,2-bis[4-(4-aminophenoxy)phenyl]hexafluoropropane
SynonymMore Synonyms

 GI-530159 Biological Activity

DescriptionGI-530159 is a selective, mechanosensitive opener of TREK1 (K2P2.1) and TREK2 (K2P10.1) channels, with an EC50 of 0.76 μM for TREK1. GI-530159 displays selectivity for TREK1/2 over TRAAK, TASK3 and other potassium channels. GI-530159 reduces rat dorsal root ganglion neuron excitability[1].
Related Catalog
Research Areas >> Neurological Disease
Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
References

[1]. Loucif AJC, et al. GI-530159, a novel, selective, mechanosensitive two-pore-domain potassium (K2P ) channel opener, reduces rat dorsal root ganglion neuron excitability. Br J Pharmacol. 2018;175(12):2272-2283.

 Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point544.8±50.0 °C at 760 mmHg
Melting Point159-163 °C(lit.)
Molecular FormulaC27H20F6N2O2
Molecular Weight518.450
Flash Point283.3±30.1 °C
Exact Mass518.142883
PSA70.50000
LogP4.57
Vapour Pressure0.0±1.5 mmHg at 25°C
Index of Refraction1.579


2. Packaging of materials

  • For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

  • For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product. 

                             Or smaller package 1kg/bottle, 10kgs/bottle as request. 


Article illustrationArticle illustration


3. Shipping & Delivery

  • By Express

Provide door to door service

Suitable for goods under 50kg

Delivery: 3-7 days

Cost: low cost

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  • By Air

Provide airport to airport service

Suitable for goods over 50kg

Delivery: 3-14 days

Cost: high cost

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  • By Sea

Provide seaport to seaport service

Suitable for goods over 100kg

Delivery: 2-45 days

Cost: low cost

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4. Contact information

For more details, pls contact us freely.

Email address: elin@fdachem.com

Mob: 86 13613820652 

WhatsApp/Skype/Wechat/LINE: 86 13613820652



Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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  • Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro
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