Product Details
| Product Name:
Fluzinamide |
CAS No.:
76263-13-3 |
| Purity:
99.67% |
Supply Ability:
10g |
| Release date:
2024/11/15 |
Product Introduction
Bioactivity
| 名稱 | Fluzinamide |
| 描述 | Fluzinamide (AHR-8559) has anticonvulsant effects on ignited amygdala seizures. |
| 體內(nèi)活性 | Extensively metabolized in mice, rats, and dogs, Fluzinamide, an antiepileptic agent effective against partial seizures, has its anticonvulsant properties evaluated in the kindled amygdaloid seizure model in rats. At doses that do not cause sedation or ataxia, Fluzinamide significantly attenuates afterdischarge durations and the severity of accompanying convulsive responses in previously kindled rats. The maximum anticonvulsant effectiveness against suprathreshold (400 μA) stimulation is observed at 30 min after acute intraperitoneal injections. Additionally, Fluzinamide (10-80 mg/kg i.p.) is assessed in kindled rats using threshold (20 μA increments) seizures. Low doses of Fluzinamide significantly elevate seizure threshold and reduce both elicited after-discharge durations and seizure severity. Administered daily during kindling acquisition, Fluzinamide (20 and 40 mg/kg i.p.) significantly increases the number of trials necessary to complete kindling. The duration and severity of responses induced by stimulations during the acquisition period are reduced [1]. |
| 存儲(chǔ)條件 | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 關(guān)鍵字 | AHR8559 | Fluzinamide | AHR 8559 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
-
CAS:103-16-2
$53.00 / 1mL
-
CAS:1247-97-8
$198.00 / 10mg
-
CAS:35337-98-5
$68.00 / 1mg
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States