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Postion:Product Catalog >Organic Chemistry>Carboxylic acids and derivatives>F-Phenibut;Cgp11130
F-Phenibut;Cgp11130
  • F-Phenibut;Cgp11130
  • F-Phenibut;Cgp11130
  • F-Phenibut;Cgp11130
  • F-Phenibut;Cgp11130
  • F-Phenibut;Cgp11130

F-Phenibut;Cgp11130

Price $10
Package 1G
Min. Order: 1G
Supply Ability: 20MT
Update Time: 2022-11-02

Product Details

Product Name: F-Phenibut;Cgp11130 CAS No.: 52237-19-1
Min. Order: 1G Purity: 99.99%
Supply Ability: 20MT Release date: 2022/11/02

Product Description

Chemical & Physical Properties:

Details :


Appearance:Solid powder

Purity:>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490

 

MedKoo Cat#: 524609 
Name: Cgp 11130 
CAS#: 52237-19-1 
Chemical Formula: C10H12FNO2 
Exact Mass: 197.08521 
Molecular Weight: 197.21 
Elemental Analysis: C, 60.90; H, 6.13; F, 9.63; N, 7.10; O, 16.23


Chemical Information

 

CAS Number:52237-19-1
Purity:≥98%
Molecular Weight:233.66 g/mol
Melting Point:Unknown
Molecular Formula:C10FH12NO2 ?HCl
Synonyms:4-Amino-3-(4-fluorophenyl)butanoic acid hydrochloride, 4-Amino-3-(4-fluorophenyl)butyric acid, Fluorophenibut HCL, F-Phenibut, Fluoribut, Fenibut
PubChem CID:103611
SMILES:C1(F)=CC=C(C=C1)C(CC(=O)O)CN


Technical Information

 

Application:F-Phenibut (Fluorophenibut) is a several-fold more potent derivative of the nootropic and anxiolytic gamma amino butyric acid derivative, Phenibut; useful as a GABAB and α2δ subunit-containing voltage-gated calcium channel ligand
Appearance:White or off-white crystalline powder
Physical State:Solid
Solubility:Freely soluble in Ethanol, Water.
Storage:Store at room temperature or cooler, in a sealed airtight container, protected from heat, light and humidity.
Stability:Stable for at least two years when stored as above.


Biochemical Activity

 

F-Phenibut (Fluorophenibut) is a several-fold more potent derivative of Phenibut. Phenibut is an atypical anxiolytic and nootropic compound structurally similar to the well known inhibitory neurotransmitter GABA, as well as to baclofen (β-(4-chlorophenyl)-GABA) and pregabalin (β-isobutyl-GABA)[1]. Phenibut was originally thought to act solely as a selective GABAB receptor agonist, similar to its much more potent relative baclofen, but has more recently been found to additionally act with somewhat higher affinity as an inhibitor of α2δ subunit-containing voltage-gated calcium channels, a mechanism of action shared with gabapentin and pregabalin.[2]

Phenibut is known to have a wider spectrum of effects than baclofen; for example Phenibut has been found to be more effective as a nootropic and neuroprotective compound than baclofen[2],[3], while baclofen has a more narrowly focused spectrum of effects and anecdotally shows a reduced tendency to induce habituation or tolerance to its effects upon chronic daily administration[4].

Preliminary (unpublished) research tentatively suggests that F-Phenibut (Fluorophenibut) has a behavioral potency of approximately five to tenfold higher than Phenibut in vivo, with approximately sixfold higher affinity as a GABAB agonist than Phenibut[5], but may also retain comparable affinity and inhibitory efficacy at α2δ subunit-containing voltage-gated calcium channels, making F-Phenibut unique as an evenly balanced ligand for these two binding sites. As an intermediary between Phenibut and baclofen, these findings hint at the potential promise that this p-fluoro relative of Phenibut might retain the broader nootropic, anxiolytic, and mood elevating characteristics of Phenibut, while simultaneously partially sharing the relatively reduced tolerance inducing properties of its p-chloro relative baclofen.

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Packaging & Shipping
 

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FAQ

 

Q: How to start orders or make payments?

A: You can send your requirement here on line,or send your purchase order by email to us, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.

Q: How to confirm the Product Quality before placing orders?

A: You can buy samples for some products,and there will be discount for sample, after testing our sample, if all is ok for you, when make bulk order, we can return the sample fee back to you, and you can also send us your requirement for some special item, we can found for you in our local market.

Q: What's your MOQ?
A: For the high value product, our MOQ starts from 1g and generally starts from 1kgs. For other low value product, our MOQ starts from 10kg and 100kg.

Q: Is there a discount?

A: Different quantity has different discount, for larger quantity, we alway support with better price.

Q: How to contact us? 

A: You can chat with us by Whatsapp & Skype & wechat Online. You can also choose your interested products and send inquiry to us. You can dial our telephone directly, you will get our reply. Send Email to us.
 
Company Profile

Hebei Ningnan Trade Co., Ltd. located in Shijiazhuang City, Hebei Province, is a large enterprise specializing in production and R & D. Our company has many years of export experience in this industry and professional logistics distribution.

We have many production lines, including industrial chemicals, pharmaceutical chemicals, chemical raw materials, fine chemicals and customized synthetic products.

We have a professional R & D team. Products are widely used in industry, rubber, textile, pharmaceutical and other industries. Products are exported to Europe, America, Southeast Asia and other countries. New and old customers are welcome to negotiate business.

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Company Profile Introduction

Hebei Ningnan Trade Co., Ltd. Located in Hebei Province, China We have strong professional research and development team, talented personnel and completely equipped laboratory for the quality controlling. We now have the most complete range of API& Pharmaceutical intermediates. We focus on doing foreign markets and and our products sell well in many countries, such as the U. S. A, the Netherlands, Poland, Canada, England, Italy, Columbia ,Southeast Asia,Middle East, South Africa and other regions.... ′Fast shipment, safety delivery′ is our advantage. We successfully shipped many Raw materials, API, Steriods, and so on, to many countries in the world. Good feedback and repeat orders support both our company and customers′ s development.

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  • Address: Yijiang Building A, No. 485, Zhonghua South Street, Qiaoxi District, Shijiazhuang City, Hebei Provin
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