Ethynodiol diacetate NEW
| Price | $35 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Ethynodiol diacetate | CAS No.: 297-76-7 |
| Purity: 99.54% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Ethynodiol diacetate |
| Description | Ethynodiol diacetate (Ethynodiol acetate) is a synthetic progestational hormone utilized alone or combined with estrogens as an oral contraceptive. |
| In vitro | Daily administration of 75 μg of Norgestrel combined with 150 μg of Ethynodiol diacetate and 7.5 μg of Ethinyl estradiol can downregulate plasma concentrations of high-density lipoprotein cholesterol in cynomolgus monkeys. Additionally, a dosage of 6 mg/kg of Ethynodiol diacetate significantly elevates the levels of 3alpha-hydroxy-5alpha-pregnan-20-one and A-homo-3-oxa-5alpha-pregnane-4,20-dione in the urine of female rats, and markedly increases the weight of the rat's pituitary, liver, and kidneys. |
| In vivo | In the presence of an S9 mix, treatment with NDGA inhibits the genotoxic damage induced by Ethynodiol diacetate, which may be attributed to the suppression of cytochrome P450s that prevent the metabolic activation of Ethynodiol diacetate, or due to NDGA's radical scavenging properties. Concurrently, 150 μg/mL Ethynodiol diacetate increases the rate of sister chromatid exchanges and the frequency of chromosomal aberrations in human lymphocytes, and inhibits lymphocyte proliferation. Notably, < 1.5 μM NDGA can reduce the rate of sister chromatid exchanges in human lymphocytes treated with 150 μg/mL Ethynodiol diacetate. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 40 mg/mL (104.03 mM) |
| Keywords | Progesterone Receptor | NR3C3 | Ethynodiol diacetate | Inhibitor | Ethynodiol Diacetate | Ethynodiol Acetate | inhibit | Ethynodiol |
| Inhibitors Related | Kaempferol | Mifepristone | Estradiol | Astragaloside IV | Estradiol benzoate | Progesterone | Estriol | Melatonin | Allura Red AC | Natamycin | Ethisterone | Estrone |
| Related Compound Libraries | Nuclear Receptor Compound Library | FDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Approved Drug Library | ReFRAME Related Library | Drug Repurposing Compound Library | NO PAINS Compound Library | FDA-Approved Drug Library | Bioactive Compounds Library Max | Human Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $35.00/500mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-11-19 | |
| $0.00/25KG |
VIP5Y
|
Hebei Mojin Biotechnology Co., Ltd
|
2024-10-11 | |
| $10.00/1kg |
Nantong Guangyuan Chemicl Co,Ltd
|
2023-11-03 | ||
| $0.00/1KG |
VIP2Y
|
Wuhan Haorong Biotechnology Co.,Ltd
|
2023-07-27 | |
| $1.00/10g |
WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
|
2020-10-23 | ||
| $0.00/1KG |
WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
|
2020-10-12 | ||
| $0.00/1KG |
WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
|
2020-09-29 | ||
| $0.00/1KG |
Hebei shuoxi biotechnology co. LTD
|
2019-10-31 | ||
| $1.00/1kg |
VIP7Y
|
Career Henan Chemical Co
|
2018-12-22 |
United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY