Epostane NEW
| Price | $623 | $1290 | $1770 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-12 |
Product Details
| Product Name: Epostane | CAS No.: 80471-63-2 |
| Purity: 100% | Supply Ability: 10g |
| Release date: 2024/11/12 |
Product Introduction
Bioactivity
| 名稱 | Epostane |
| 描述 | Epostane acts as an antiprogestogen and terminates pregnancy by inhibiting 3β-hydroxysteroid dehydrogenase and preventing the biosynthesis of progesterone and pregnenolone. [4] |
| 體外活性 | METHODS: Using one fish oocyte, the ovary was cut into small pieces and incubated with Epostane (1 μg/mL), and the incidence of germinal vesicle breakdown (GVBD) was examined microscopically RESULTS Epostane induced a significant decrease in the frequency of GVBD in oocytes, but Epostane failed to eliminate the maturation effect of 17α,20 β-diOHprog, the most potent maturation-inducing steroid in this species. |
| 體內(nèi)活性 | METHODS: A single-dose, randomized, double-blind study was conducted in which each woman awaiting termination of pregnancy was administered either 50 mg Epostane or 100 mg Epostane orally, and the effects of in vivo serum luteinizing hormone (P), estradiol (E2), and cortisol were determined. RESULTS Both serum P concentrations decreased significantly, and a similar decrease in serum E2 was observed, with subsequent normalization of E2. [1] METHODS: Seventy-eight healthy women were recruited to the study who were less than 49 days from their last menstrual period and requested termination of pregnancy, 200 mg Epostane four times daily for a total of 7 days. RESULTS The complete abortion rate in the Epostane group was 73%. [2] |
| 存儲條件 | Shipping with blue ice. |
| 關(guān)鍵字 | Win 32729 | Epostane | Win32729 |
| 相關(guān)產(chǎn)品 | Disulfiram | Methotrexate | Rotenone | Mycophenolate Mofetil | Ribavirin | 4-Diethylaminobenzaldehyde | Benzyl alcohol | Isomalt | Isoniazid | Ivosidenib |
| 相關(guān)庫 | 經(jīng)典已知活性庫 | 抑制劑庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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