Product Details
| Product Name:
Eperezolid |
CAS No.:
165800-04-4 |
| Purity:
96.18% |
Supply Ability:
10g |
| Release date:
2024/11/14 |
Product Introduction
Bioactivity
| 名稱 | Eperezolid |
| 描述 | Eperezolid (PNU-100592) is an oxazolidinone antibacterial agent. Eperezolid showed well in vitro inhibitory activity, regardless of methicillin susceptibility for staphylococci(MIC90= 1-4 mg/ml). |
| 體外活性 | The specific binding of eperezolid is dose-dependent and is proportional to the ribosome concentrations. The binding of eperezolid to the ribosome is competitively inhibited by chloramphenicol and lincomycin. However, unlike chloramphenicol and lincomycin, eperezolid does not inhibit the puromycin reaction, indicating that the oxazolidinones have no effect on peptidyl transferase [2]. Antibiotic Eperezolid binds specifically to the 50S ribosomal subunit of Escherichia coli. eperezolid was found to bind only to the 50S subunit, with similar affinity as to the 70S ribosome, and to have no affinity for the 30S subunit [3]. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 40 mg/mL (101.42 mM), Sonication is recommended.
|
| 關(guān)鍵字 | Bacterial | Eperezolid | PNU 100592 | Inhibitor | PNU100592 | inhibit | Antibiotic |
| 相關(guān)產(chǎn)品 | Neomycin sulfate | Dehydroacetic acid sodium | Ampicillin sodium | Methyl anthranilate | Kanamycin sulfate | G-418 disulfate | Sulfamethoxazole sodium | Metronidazole | Doxycycline | EDTA copper(II) disodium salt | Dimethyl sulfoxide | Crystal Violet |
| 相關(guān)庫(kù) | 經(jīng)典已知活性庫(kù) | ReFRAME 相關(guān)化合物庫(kù) | 抗生素庫(kù) | 抑制劑庫(kù) | 抗菌活性庫(kù) | 已知活性化合物庫(kù) | 抗感染化合物庫(kù) | 人代謝物化合物庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States