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Postion:Product Catalog >API>Antibiotics>Peptides drug>Enramycin
Enramycin
  • Enramycin
  • Enramycin
  • Enramycin
  • Enramycin
  • Enramycin

Enramycin NEW

Price Get Latest Price
Package 1kg
Min. Order: 1kg
Supply Ability: 1000kg
Update Time: 2024-04-02

Product Details

Product Name: Enramycin CAS No.: 11115-82-5
EC-No.: 695-076-0 Min. Order: 1kg
Purity: 99% Supply Ability: 1000kg
Release date: 2024/04/02

Manufacturer Provide Pharmaceutical Chemicals Veterinary Raw Material CAS11115-82-5 Enramycin


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Introduction

1.Product Name: Enramycin

2.Other Name :ENDURACIDIN HYDROCHLORIDE

3.CAS NO:11115-82-5

4.Purity: 99%min
5.Appearance:White Crystalline Powder

6.Molecular formula:C106H135Cl2N26O31R

7.Molecular weight:2340.2677

8.Storage:Keep in dark place,Sealed in dry,2-8°C


Enramycin is a polypeptide antibiotic that binds unsaturated fatty acids to more than a dozen amino acids. The main components are Enramycin A and B, which are its hydrochloride forms. application. White or yellowish white powder(coarse gray or gray-brown powder with extra odor). 234 ~ 238 °C decomposition, soluble in dilute hydrochloric acid, slightly soluble in water, methanol, ethanol, insoluble in acetone.


Function 
Enramycin has a strong activity against Gram-positive bacteria, especially Clostridium in the intestine. After long-term use, it is not easy to develop drug resistance because it changes the bacterial population in the intestine. Therefore, the use of nutrients in feed is good, which can promote weight gain in pigs and chickens and increase feed conversion rates. Enramycin oral LD50 was 10g per kilogram of weight in large mice and 522.9 mg in 4 weeks of age. However, Enramycin(crude crystal) used for feed addition was oral, 11 g per kg of body weight in rats and mice and 8 g in broilers. Teratogenic and mutagenicity tests were negative. After oral administration, Enramycin only plays a role in the digestive tract and is not easily absorbed. After 6 to 12 H of administration of the chicken, enramycin excreted in the faeces reached 87.0 % to 100 %, and the residue of the piglets was very small. After 1 week of continuous use, the residue in the tissues was less than 25 μg / kg on the same day. Enramycin has no toxic effect on crops, fish and the environment after it is discharged by chickens and pigs. Therefore, it is a safe and effective animal specific antibiotic. Enramycin is preserved at 40 °C for 4 months, and the price is still above 90 %, but the price is reduced when the humidity is high. Enramycin is stored at room temperature for 12 weeks in the added feed, and the potency is not less than 90 % .


Application 
1) Enramycin has a strong effect on Gram-positive bacteria. The main mechanism is to inhibit the synthesis of bacterial cell walls. The bacterial cell wall is mainly to maintain the appearance and maintain osmotic pressure stability. Its main component is viscous peptides. In Gram-positive bacteria, viscous peptides account for 65-95 % of the total cell wall. Enramycin can prevent the synthesis of sticky peptides, causing cell wall defects, causing intracellular osmotic pressure to increase, extracellular fluids to infiltrate the bacteria, causing bacteria to deform and swell, rupture and die. Enramycin mainly acts on the cracking stage of bacteria, not only sterilizing but also dissolving bacteria. The minimum antibacterial concentration is 0.05-3.13 μg / ml
2) The antibacterial ability of Enramycin to Clostridium aeruginosa is common in feeds. It can damage the small intestine, aggravate the severity of coccidiasis, and reduce the production performance of livestock and poultry. It is one of the main causes of chicken water stool, necrotizing enteritis and porcine diarrhea, and has become a universal concern in the world. It was found that Enramycin had the strongest antibacterial ability and no resistant strains were found in the test of Clostridium aeruginosa isolated from chicken farm by several progrowth antibiotics.


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Company Profile Introduction

Shaanxi TNJONE Pharmaceutical Co., Ltd supplies more than 2,000 kinds of products, covering the whole field of health industry, including human APIs, veterinary APIs, food additives, natural nutrition ingredients, feed additives, cosmetic additives, intermediates etc. With global sourcing advantages, the group is fully capable of meeting the one-stop sourcing needs of global customers. Today, Shaanxi TNJONE Pharmaceutical Co., Ltd.'s marketing network has spread over more than 100 countries and regions on five continents, providing professional service for global customers.

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Shaanxi TNJONE Pharmaceutical Co., Ltd

1YR ChinaChina
  • Since: 2019-05-23
  • Address: No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New C
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