ELOVL6-IN-3 NEW
| Price | Get Latest Price | |
| Package | 5mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-11 |
Product Details
| Product Name: ELOVL6-IN-3 | CAS No.: 712346-06-0 |
| Supply Ability: 10g | Release date: 2024/11/11 |
Product Introduction
Bioactivity
| 名稱 | ELOVL6-IN-3 |
| 描述 | ELOVL6-IN-1 is a potent, selective, and orally active inhibitor of ELOVL6, exhibiting dose-dependent inhibition of mouse ELOVL6 with an IC50 of 0.350 μM and acting as a noncompetitive inhibitor with respect to malonyl-CoA (Ki=994 nM) and palmitoyl-CoA [1]. |
| 體外活性 | ELOVL6-IN-1 possesses adequate lipophilicity, enabling it to potentially penetrate intracellular spaces via passive diffusion [1]. |
| 體內(nèi)活性 | ELOVL6-IN-1, administered orally at a dosage of 10 mg/kg for a duration of 0 to 2 hours, demonstrated significant exposure in both plasma and liver [1]. At dosages of 10 and 30 mg/kg, also administered orally and within the same two-hour time frame, it reduced the elongation index of hepatic lipids [1]. Moreover, when given at a higher dose of 100 mg/kg over a two-day period, ELOVL6-IN-1 decreased the total fatty acid elongation index in the liver [1]. |
| 存儲(chǔ)條件 | Shipping with blue ice. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $33.00/5mg |
VIP5Y
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TargetMol Chemicals Inc.
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2024-11-11 | |
| $3400.00/100mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-10-23 | |
| $1.00/1KG |
VIP7Y
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.GZ HONESTCHEM CO.,LTD
|
2018-09-12 |
United States- Since: 2011-01-07
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