Dyclonine hydrochloride
| Price | $400 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | Ex 20 tons |
| Update Time: | 2022-09-16 |
Product Details
| Product Name: Dyclonine hydrochloride | CAS No.: 536-43-6 |
| EC-No.: 208-633-6 | Min. Order: 1KG |
| Purity: 99% | Supply Ability: Ex 20 tons |
| Release date: 2022/09/16 |
| Description | Dyclonine is an oral anaesthetic found in Sucrets, an over the counter throat lozenge.Target: Sodium ChannelDyclonine is an oral anaesthetic that is the active ingredient of Sucrets, an over the counter throat lozenge. It is also found in some varieties of the Cepacol sore throat spray. It is a local anesthetic, used topically as the hydrochloride salt. Dyclonine hydrochloride has been found to possess, in addition to its topical anesthetic properties, significant bactericidal and fungicidal activity. Self-sterilizing action manifested by preparations containing the drug was considerably enhanced upon the addition of chlorobutanol. Results of in vitro tests employing microorganisms commonly involved in local infections indicated that the two agents in combination act synergistically [1, 2]. |
|---|---|
| Related Catalog | Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Neurological Disease |
| Solvent | In Vitro: 10 mM in DMSO |
| Solubility | 1 mM3.0687 mL15.3435 mL30.6871 mL5 mM0.6137 mL3.0687 mL6.1374 mL10 mM0.3069 mL1.5344 mL3.0687 mL |
| Storage | Powder-20°C3 years 4°C2 yearsIn solvent-80°C6 months -20°C1 month |
| Shipping | Room temperature in continental US; may vary elsewhere |
| SMILES | O=C(C1=CC=C(OCCCC)C=C1)CCN2CCCCC2.Cl |
| References | [1]. Florestano, H.J. and M.E. Bahler, Antimicrobial properties of dyclonine hydrochloride, a new topical anesthetic. J Am Pharm Assoc Am Pharm Assoc (Baltim), 1956. 45(5): p. 320-5. [2]. Gargiulo, A.V., G.M. Burns, and C.P. Huck, Dyclonine hydrochloride--a topical agent for managing pain. Ill Dent J, 1992. 61(4): p. 303-4. |
| Related Molecules | EIPA | Riluzole | Ginsenoside Rg3 | Cariporide | Eleclazine hydrochloride | GS967 | Tenapanor | Triamterene | Ranolazine dihydrochloride | PF 05089771 | flecainide acetate | A-803467 | CNV1014802 (hydrochloride) | Zonisamide | Cinchocaine |
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China- Since: 2022-02-24
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