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Postion:Product Catalog >API>Digestive system drugs>Gastrointestinal antispasmodic drugs>Drotaverine hydrochloride
Drotaverine hydrochloride
  • Drotaverine hydrochloride

Drotaverine hydrochloride NEW

Price $47 $72 $139
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-04-30

Product Details

Product Name: Drotaverine hydrochloride CAS No.: 985-12-6
Purity: 99.81% Supply Ability: 10g
Release date: 2025/04/30

Product Introduction

Bioactivity

NameDrotaverine hydrochloride
DescriptionDrotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor,and is an antispasmodic drug, used to enhance cervical dilation during childbirth. Drotaverine hydrochloride is structurally related to papaverine
In vitrodrotaverine not only relaxed the precontracted tracheal preparations but also decreased mediator-induced contraction.?These effects of drotaverine were concentration dependent, with a significantly higher potency on the KCl-induced response, than on either the histamine or methacholine induced one.?A similar result was noted for nifedipine.?The PDE inhibitor, theophylline, also relaxed the precontracted preparations but was ineffective on the mediator-induced contraction in a physiologically relevant concentration range.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 25 mg/mL (57.61 mM), Sonication is recommended.
KeywordsPhosphodiesterase (PDE) | PDE4 | Inhibitor | inhibit | Drotaverine hydrochloride | Drotaverine Hydrochloride | Drotaverine | Calcium Channel | Ca2+ channels | Ca channels
Inhibitors RelatedTheophylline monohydrate | Acefylline | Roflumilast | Theobromine | Apremilast | Isoprenaline hydrochloride | Indomethacin | Icariin | Theophylline | Vardenafil hydrochloride | Doxofylline | Sildenafil citrate
Related Compound LibrariesFDA-Approved & Pharmacopeia Drug Library | Failed Clinical Trials Compound Library | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | ReFRAME Related Library | Drug Repurposing Compound Library | Neuroprotective Compound Library | Inhibitor Library | NO PAINS Compound Library | RO5 Drug-like Natural Product Library | Bioactive Compounds Library Max | Anti-Metabolism Disease Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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