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Postion:Product Catalog >API>Antineoplastic agents>Hormonal antineoplastic drugs>Droloxifene
Droloxifene
  • Droloxifene

Droloxifene NEW

Price $49 $118 $178
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-11

Product Details

Product Name: Droloxifene CAS No.: 82413-20-5
Purity: 99.37% Supply Ability: 10g
Release date: 2024/11/11

Product Introduction

Bioactivity

名稱(chēng)Droloxifene
描述Droloxifene (3-Hydroxytamoxifen), a tamoxifen derivative, is an oral active and selective estrogen receptor modulator.Droloxifene induced p53 expression and apoptosis in McF-7 cells.Fluroxifene has anti-estrogen and anti-implantation effects.Fluroxifene prevented bone loss in ovariectomized rats.
體外活性Droloxifene induces apoptosis in MCF-7 cells(10 nM; 16-18 hours)[1].
體內(nèi)活性Droloxifene (5-20 mg/kg,P.o.;Daily for 4 weeks can bring THE BMD of DFM up to 10mg/kg and completely prevent OVX from reducing the BMC and BMD of DFM at 20mg /kg/day[1].
存儲(chǔ)條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 40 mg/mL (103.22 mM), Sonication is recommended.
關(guān)鍵字Droloxifene
相關(guān)產(chǎn)品Kaempferol | Tamoxifen | Estradiol | Estradiol benzoate | ARV-471 | Cholesterol | Estriol | Chrysin | Ethisterone | Estrone
相關(guān)庫(kù)核受體化合物庫(kù) | 經(jīng)典已知活性庫(kù) | 抗卵巢癌化合物庫(kù) | 已知活性化合物庫(kù) | 抗癌化合物庫(kù)

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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