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Postion:Product Catalog >DOV-216,303 Free Base
DOV-216,303 Free Base
  • DOV-216,303 Free Base

DOV-216,303 Free Base NEW

Price $60 $98 $162
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-11

Product Details

Product Name: DOV-216,303 Free Base CAS No.: 66504-40-3
Purity: 96.7% Supply Ability: 10g
Release date: 2024/11/11

Product Introduction

Bioactivity

名稱DOV-216,303 Free Base
描述DOV-216,303 Free Base (DOV-216303) is an inhibitor of serotonin, norepinephrine, and dopamine reuptake with with IC50s of 14, 20 and 78 nM. DOV-216,303 Free Base exhibits antidepressant effects.
體內(nèi)活性In male Sprague Dawley rats of OBX or Sham surgery, DOV 216,303 (20 mg/kg; i.p.; choronic) increases extracellular concentrations of dopamine, norepinephrine and serotonin and significantly increases extracellular baseline serotonin concentrations while DOV-216,303 (20 mg/kg; i.p.; acute) significantly increases dopamine, norepinephrine and serotonin levels[2].
存儲(chǔ)條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 125 mg/mL (547.96 mM)
Ethanol : 95 mg/mL (416.45 mM), Sonication is recommended.
關(guān)鍵字inhibit | SLC6A4 | Serotonin Transporter | DOV 216303 | DOV 216,303 Free Base | DOV-216,303 Free Base | 5-HTT | DAT | DOV216303 | SERT | Dopamine Transporter | SLC6A3 | Inhibitor | DOV-216,303 | DOV216,303 Free Base
相關(guān)產(chǎn)品Olanzapine | Dapoxetine hydrochloride | CLOZAPINE N-OXIDE | Mirtazapine | Octopamine hydrochloride | Octodrine | Citicoline | Amitriptyline hydrochloride | Oxolinic acid | Mianserin hydrochloride | Fluoxetine hydrochloride | Cinchonidine
相關(guān)庫(kù)神經(jīng)退行性疾病化合物庫(kù) | 經(jīng)典已知活性庫(kù) | 神經(jīng)信號(hào)分子庫(kù) | 抗抑郁癥化合物庫(kù) | 膜蛋白靶向化合物庫(kù) | ReFRAME 相關(guān)化合物庫(kù) | 神經(jīng)遞質(zhì)受體化合物庫(kù) | 抑制劑庫(kù) | 已知活性化合物庫(kù) | GPCR靶點(diǎn)分子庫(kù)

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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