Product Details
Product Name:
DOPEXAMINE |
CAS No.:
86197-47-9 |
Purity:
99.42% |
Supply Ability:
10g |
Release date:
2024/11/15 |
Product Introduction
Bioactivity
名稱 | DOPEXAMINE |
描述 | Dopexamine is a dopaminergic agonist |
體內(nèi)活性 | Dopexamine hydrochloride has interesting vasodilator properties, with marked intrinsic agonist activity at beta-2 adrenoreceptors and a lesser agonist activity at dopaminergic receptors (DA1 and DA2).?Dopexamine hydrochloride is responsible for an inhibition of neuronal re-uptake of catecholamines (uptake-1), producing an indirect stimulation of cardiac beta 1-receptors.?Dopexamine hydrochloride improves cardiac performance by a marked vasodilation and a mild inotropic activity.?The specific activity at dopaminergic receptors increases cerebral, myocardial, splanchnic and renal blood flows.?These haemodynamic effects are associated with an increase in diuresis and natriuresis.?These benefits are achieved without side effects such as an increased myocardial oxygen consumption, although induced tachycardia may be responsible for chest pain/anginae pain in patients with ischaemic heart disease[1]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 55 mg/ml (154.28 mM)
|
關(guān)鍵字 | DOPEXAMINE |
相關(guān)產(chǎn)品 | Olanzapine | CLOZAPINE N-OXIDE | Mirtazapine | Octopamine hydrochloride | Octodrine | Citicoline | Phenothiazine | Oxolinic acid | Mianserin hydrochloride | Doxepin hydrochloride |
相關(guān)庫 | 神經(jīng)退行性疾病化合物庫 | 經(jīng)典已知活性庫 | 抗抑郁癥化合物庫 | 神經(jīng)信號分子庫 | 膜蛋白靶向化合物庫 | ReFRAME 相關(guān)化合物庫 | 抗帕金森病化合物庫 | 已知活性化合物庫 | GPCR靶點分子庫 | 人代謝物化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$48.00/1mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-11-14 |