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Postion:Product Catalog >API>Circulatory system drugs>Anti Shock vasoactive drugs>Dopamine hydrochloride
Dopamine hydrochloride
  • Dopamine hydrochloride
  • Dopamine hydrochloride

Dopamine hydrochloride NEW

Price $6 $0.2
Package 1KG 1000KG
Min. Order: 1KG
Supply Ability: g-kg-tons, free sample is available
Update Time: 2024-03-29

Product Details

Product Name: Dopamine hydrochloride CAS No.: 62-31-7
Min. Order: 1KG Purity: 99%
Supply Ability: g-kg-tons, free sample is available Release date: 2024/03/29
Lead time: In stock, ready for shipment Packaging: bag/bottle/drum/IBC
Delivery: By express, by air, by sea Origin: Manufacturer, advantage product
COA, MSDS: Available, contact us for details Name: Tina

 1. Materials information


Names

Name3-Hydroxytyramine hydrochloride
SynonymMore Synonyms

 Dopamine hydrochloride Biological Activity

DescriptionDopamine HCl is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist.Target: Dopamine ReceptorDopamine (or 3,4-dihydroxyphenethylamine) is a neuroendocrine transmitter in the catecholamine and phenethylamine families that plays a number of important roles in the brain and bodies of humans. Several important diseases of the nervous system are associated with dysfunctions of the dopamine system. Outside the nervous system, dopamine functions in several parts of the body as a local chemical messenger. In the blood vessels, it inhibits norepinephrine release and acts as a vasodilator; in the kidneys, it increases sodium excretion and urine output; in the pancreas, it reduces insulin production; in the digestive system, it reduces gastrointestinal motility and protects intestinal mucosa; and in the immune system, it reduces the activity of lymphocytes. A variety of important drugs work by altering the way the body makes or uses dopamine. Dopamine itself is available for intravenous injection: although it cannot reach the brain from the bloodstream, its peripheral effects make it useful in the treatment of heart failure or shock, especially in newborn babies. L-DOPA, the metabolic precursor of dopamine, does reach the brain and is the most widely used treatment for Parkinson's disease. From Wikipedia.
Related Catalog
Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor
Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor
Natural Products >> Others
Research Areas >> Neurological Disease
Target

Human Endogenous Metabolite

References

[1]. http://en.wikipedia.org/wiki/Dopamine

 Chemical & Physical Properties

Boiling Point337.7oC at 760 mmHg
Melting Point248-250 °C(lit.)
Molecular FormulaC8H12ClNO2
Molecular Weight189.639
Exact Mass189.055649
PSA66.48000
LogP2.10130
StabilityStable. Incompatible with strong oxidizing agents. Combustible.
Water Solubilitysoluble

 MSDS

Dopamine hydrochloride MSDS(Chinese)

 Toxicological Information

CHEMICAL IDENTIFICATION

  • RTECS NUMBER :

  • UX1092000

  • CHEMICAL NAME :

  • Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride

  • CAS REGISTRY NUMBER :

  • 62-31-7

  • LAST UPDATED :

  • 199701

  • DATA ITEMS CITED :

  • 22

  • MOLECULAR FORMULA :

  • C8-H11-N-O2.Cl-H

  • MOLECULAR WEIGHT :

  • 189.66

  • WISWESSER LINE NOTATION :

  • Z2R CQ DQ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Oral

  • SPECIES OBSERVED :

  • Rodent - rat

  • DOSE/DURATION :

  • 2859 mg/kg

  • TOXIC EFFECTS :

  • Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Intraperitoneal

  • SPECIES OBSERVED :

  • Rodent - rat

  • DOSE/DURATION :

  • 597 mg/kg

  • TOXIC EFFECTS :

  • Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Subcutaneous

  • SPECIES OBSERVED :

  • Rodent - rat

  • DOSE/DURATION :

  • 647 mg/kg

  • TOXIC EFFECTS :

  • Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Intravenous

  • SPECIES OBSERVED :

  • Rodent - rat

  • DOSE/DURATION :

  • 4800 ug/kg

  • TOXIC EFFECTS :

  • Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Oral

  • SPECIES OBSERVED :

  • Rodent - mouse

  • DOSE/DURATION :

  • 4361 mg/kg

  • TOXIC EFFECTS :

  • Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Intraperitoneal

  • SPECIES OBSERVED :

  • Rodent - mouse

  • DOSE/DURATION :

  • 914 mg/kg

  • TOXIC EFFECTS :

  • Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Subcutaneous

  • SPECIES OBSERVED :

  • Rodent - mouse

  • DOSE/DURATION :

  • 1366 mg/kg

  • TOXIC EFFECTS :

  • Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Intravenous

  • SPECIES OBSERVED :

  • Rodent - mouse

  • DOSE/DURATION :

  • 156 mg/kg

  • TOXIC EFFECTS :

  • Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Intravenous

  • SPECIES OBSERVED :

  • Mammal - dog

  • DOSE/DURATION :

  • 79 mg/kg

  • TOXIC EFFECTS :

  • Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - ataxia Gastrointestinal - hypermotility, diarrhea

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Intravenous

  • SPECIES OBSERVED :

  • Rodent - rabbit

  • DOSE/DURATION :

  • 90 mg/kg

  • TOXIC EFFECTS :

  • Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

  • TYPE OF TEST :

  • TDLo - Lowest published toxic dose

  • ROUTE OF EXPOSURE :

  • Intravenous

  • SPECIES OBSERVED :

  • Rodent - rat

  • DOSE/DURATION :

  • 420 mg/kg/6W-I

  • TOXIC EFFECTS :

  • Cardiac - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

  • TYPE OF TEST :

  • TDLo - Lowest published toxic dose

  • ROUTE OF EXPOSURE :

  • Intravenous

  • SPECIES OBSERVED :

  • Mammal - dog

  • DOSE/DURATION :

  • 42 mg/kg/6W-I

  • TOXIC EFFECTS :

  • Cardiac - pulse rate increase, without fall in BP Cardiac - pulse rate

  • TYPE OF TEST :

  • TDLo - Lowest published toxic dose

  • ROUTE OF EXPOSURE :

  • Intraperitoneal

  • DOSE :

  • 7 mg/kg

  • SEX/DURATION :

  • female 1-7 day(s) after conception

  • TOXIC EFFECTS :

  • Reproductive - Specific Developmental Abnormalities - other developmental abnormalities

  • TYPE OF TEST :

  • TDLo - Lowest published toxic dose

  • ROUTE OF EXPOSURE :

  • Intraperitoneal

  • DOSE :

  • 2100 ug/kg

  • SEX/DURATION :

  • female 7-12 day(s) after conception

  • TOXIC EFFECTS :

  • Reproductive - Specific Developmental Abnormalities - musculoskeletal system

  • TYPE OF TEST :

  • TDLo - Lowest published toxic dose

  • ROUTE OF EXPOSURE :

  • Intravenous

  • DOSE :

  • 300 mg/kg

  • SEX/DURATION :

  • female 6-15 day(s) after conception

  • TOXIC EFFECTS :

  • Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

  • TYPE OF TEST :

  • TDLo - Lowest published toxic dose

  • ROUTE OF EXPOSURE :

  • Intravenous

  • DOSE :

  • 900 mg/kg

  • SEX/DURATION :

  • female 6-15 day(s) after conception

  • TOXIC EFFECTS :

  • Reproductive - Specific Developmental Abnormalities - musculoskeletal system

  • TYPE OF TEST :

  • TDLo - Lowest published toxic dose

  • ROUTE OF EXPOSURE :

  • Intravenous

  • DOSE :

  • 361 mg/kg

  • SEX/DURATION :

  • female 15 week(s) after conception

  • TOXIC EFFECTS :

  • Reproductive - Specific Developmental Abnormalities - blood and lymphatic systems (including spleen and marrow)

MUTATION DATA

  • TYPE OF TEST :

  • Mutation in mammalian somatic cells

  • TEST SYSTEM :

  • Rodent - mouse Lymphocyte

  • DOSE/DURATION :

  • 93800 ug/L

  • REFERENCE :

  • MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 124,9,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3889 No. of Facilities: 135 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 5239 (estimated) No. of Female Employees: 3875 (estimated)

 Safety Information

SymbolArticle illustration Article illustration
GHS07, GHS09
Signal WordWarning
Hazard StatementsH302-H410
Precautionary StatementsP273-P501
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXi:Irritant
Risk PhrasesR36/37/38
Safety PhrasesS26-S36
RIDADRUN 3077 9/PG 3
WGK Germany2
RTECSUX1092000
HS Code29222900
Flash Point(F)51.8 °F
Flash Point(C)11 °C

 Synthetic Route

Previous 1/2 Next
Article illustration

TRANS-3 4-BENZY...

CAS#:1699-54-3

~96%

Article illustration

Dopamine hydroc...

CAS#:62-31-7

Literature: Kohno; Sasao; Murahashi Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 4 p. 1252 - 1254
Article illustration

3,4-Dimethoxyph...

CAS#:120-20-7

~76%

Article illustration

Dopamine hydroc...

CAS#:62-31-7

Literature: Velcicky, Juraj; Soicke, Arne; Steiner, Roland; Schmalz, Hans-Guenther Journal of the American Chemical Society, 2011 , vol. 133, # 18 p. 6948 - 6951
Article illustration

tert-butyl N-[2...

CAS#:37034-31-4

~99%

Article illustration

Dopamine hydroc...

CAS#:62-31-7

Literature: Bernini, Roberta; Crisante, Fernanda; Barontini, Maurizio; Fabrizi, Giancarlo Synthesis, 2009 , # 22 art. no. P09409SS, p. 3838 - 3842

 Precursor & DownStream

Precursor  4


  • Article illustration CAS#:1699-54-3
    TRANS-3 4-BENZY...

  • Article illustration CAS#:120-20-7
    3,4-Dimethoxyph...

  • Article illustration CAS#:37034-31-4
    tert-butyl N-[2...

  • Article illustration CAS#:93-17-4
    3,4-Dimethoxyph...

DownStream  10

Previous 1/3 Next

  • Article illustration CAS#:105955-13-3
    N-[2-(3,4-dihyd...

  • Article illustration CAS#:105955-12-2
    N-linoleoyldopamine

  • Article illustration CAS#:105955-10-0
    STEARDA

  • Article illustration CAS#:105955-11-1
    OLDA

 Customs

HS Code29222900


2. Packaging of materials

  • For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

  • For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product. 

                             Or smaller package 1kg/bottle, 10kgs/bottle as request. 


Article illustrationArticle illustration


3. Shipping & Delivery

  • By Express

Provide door to door service

Suitable for goods under 50kg

Delivery: 3-7 days

Cost: low cost

Article illustration


  • By Air

Provide airport to airport service

Suitable for goods over 50kg

Delivery: 3-14 days

Cost: high cost

Article illustration


  • By Sea

Provide seaport to seaport service

Suitable for goods over 100kg

Delivery: 2-45 days

Cost: low cost

Article illustration


4. Contact information

For more details, pls contact us freely.

Email address: Tina@fdachem.com

Mob: 86 15225627621

WhatsApp/Skype/Wechat/LINE: 86 15225627621









Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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  • Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro
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