Diphenmanil methylsulfate NEW
| Price | $38 | $47 | $62 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-14 |
Product Details
| Product Name: Diphenmanil methylsulfate | CAS No.: 62-97-5 |
| Purity: 99.85% | Supply Ability: 10g |
| Release date: 2024/11/14 |
Product Introduction
Bioactivity
| 名稱 | Diphenmanil methylsulfate |
| 描述 | Diphenmanil methylsulfate (Diphemanil mesylate), a quaternary ammonium anticholinergic, binds muscarinic acetylcholine receptors and thus decreases secretory excretion of stomach acids, sweat, and saliva. |
| 體外活性 | Pharmacokinetic studies indicate that Diphemanil Methylsulphate is slowly absorbed, with a peak time (tmax) of 2-4 hours and an average half-life of 8.35 hours. Within 48 hours, 0.6%-7.4% of the administered dose is recovered in the urine. The compound exhibits poor gastrointestinal absorption, with bioavailability ranging from 15% to 25%. |
| 體內(nèi)活性 | Diphemanil Methylsulfate exerts its anticholinergic effects primarily by binding to muscarinic M3 receptors, and it also acts directly on smooth muscle to provide antispasmodic benefits. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 50 mg/mL (128.37 mM), Sonication is recommended. H2O : 26 mg/mL (66.8 mM) Ethanol : < 1 mg/mL (insoluble or slightly soluble) |
| 關鍵字 | Diphemanil | Diphemanil Mesylate | Muscarinic acetylcholine receptor | Diphenmanil | Inhibitor | mAChR | Diphenmanil methylsulfate | inhibit |
| 相關產(chǎn)品 | Adiphenine hydrochloride | Nanofin | Arecoline hydrobromide | Forskolin | CLOZAPINE N-OXIDE | Pilocarpine nitrate | Ribavirin | Adenine | Choline chloride | Propoxur |
| 相關庫 | 經(jīng)典已知活性庫 | 神經(jīng)退行性疾病化合物庫 | 神經(jīng)信號分子庫 | 抗阿爾茨海默癥化合物庫 | 膜蛋白靶向化合物庫 | 神經(jīng)遞質(zhì)受體化合物庫 | 藥物功能重定位化合物庫 | NO PAINS 化合物庫 | FDA 上市藥物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $38.00/25mg |
VIP5Y
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TargetMol Chemicals Inc.
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2024-11-14 | |
| $12.00/1KG |
Hong Kong Tiansheng New Material Trading Co., Ltd
|
2021-09-24 | ||
| $12.00/1KG |
Hong Kong Tiansheng New Material Trading Co., Ltd
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2021-09-24 |
United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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