Dimethyl biphenyl-4,4'-dicarboxylate NEW
Price | $29 |
Package | 100mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-11 |
Product Details
Product Name: Dimethyl biphenyl-4,4'-dicarboxylate | CAS No.: 792-74-5 |
Purity: 98.37% | Supply Ability: 10g |
Release date: 2024/11/11 |
Product Introduction
Bioactivity
名稱 | Dimethyl biphenyl-4,4'-dicarboxylate |
描述 | Dimethyl biphenyl-4,4'-dicarboxylate (Biphenyl dimethyl dicarboxylate) is a planar biphenyldicarboxylic acid ester utilized as a hepatoprotectant for chronic hepatitis treatment. |
體外活性 | Dimethyl biphenyl-4,4'-dicarboxylate(DDB) (200 ug/10(6) cells) efficiently protected the hepatocytes against carbon tetrachloride (10 mM) and D-galactosamine (1 mM) induced damages.?Membrane lipid peroxidation (malondialdehyde, MDA) formation and Glutamic Pyruvic Transaminase (GPT) released from the hepatocytes were markedly decreased.?The damage of the cell surfaces of the hepatocytes were also reduced as seen under a scanning electron microscope (SEM)[1]. |
體內(nèi)活性 | Pretreatment with DDB (300 mg/kg) orally could ameliorate the reduction of liver glycogen and blood glucose caused by injection of D-gal (800 mg/kg i. p) in mice.?When normal rats received 300 mg/kg of DDB once daily for 10 days, free ribosomal protein and RNA in the liver increased significantly[1]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | H2O : 2.5 mM DMSO : Insoluble |
關(guān)鍵字 | Dimethyl biphenyl4,4'dicarboxylate | Dimethyl biphenyl 4,4' dicarboxylate | inhibit | Dimethyl biphenyl-4,4'-dicarboxylate | Inhibitor |
相關(guān)庫 | 經(jīng)典已知活性庫 | 內(nèi)質(zhì)網(wǎng)應(yīng)激化合物庫 | NO PAINS 化合物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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