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Postion:Product Catalog >Chemical Reagents>Organic reagents>Esters>Methyl ester compound>Dimethyl biphenyl-4,4'-dicarboxylate
Dimethyl biphenyl-4,4'-dicarboxylate
  • Dimethyl biphenyl-4,4'-dicarboxylate

Dimethyl biphenyl-4,4'-dicarboxylate NEW

Price $29
Package 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-11

Product Details

Product Name: Dimethyl biphenyl-4,4'-dicarboxylate CAS No.: 792-74-5
Purity: 98.37% Supply Ability: 10g
Release date: 2024/11/11

Product Introduction

Bioactivity

名稱Dimethyl biphenyl-4,4'-dicarboxylate
描述Dimethyl biphenyl-4,4'-dicarboxylate (Biphenyl dimethyl dicarboxylate) is a planar biphenyldicarboxylic acid ester utilized as a hepatoprotectant for chronic hepatitis treatment.
體外活性Dimethyl biphenyl-4,4'-dicarboxylate(DDB) (200 ug/10(6) cells) efficiently protected the hepatocytes against carbon tetrachloride (10 mM) and D-galactosamine (1 mM) induced damages.?Membrane lipid peroxidation (malondialdehyde, MDA) formation and Glutamic Pyruvic Transaminase (GPT) released from the hepatocytes were markedly decreased.?The damage of the cell surfaces of the hepatocytes were also reduced as seen under a scanning electron microscope (SEM)[1].
體內(nèi)活性Pretreatment with DDB (300 mg/kg) orally could ameliorate the reduction of liver glycogen and blood glucose caused by injection of D-gal (800 mg/kg i. p) in mice.?When normal rats received 300 mg/kg of DDB once daily for 10 days, free ribosomal protein and RNA in the liver increased significantly[1].
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度H2O : 2.5 mM
DMSO : Insoluble
關(guān)鍵字Dimethyl biphenyl4,4'dicarboxylate | Dimethyl biphenyl 4,4' dicarboxylate | inhibit | Dimethyl biphenyl-4,4'-dicarboxylate | Inhibitor
相關(guān)庫經(jīng)典已知活性庫 | 內(nèi)質(zhì)網(wǎng)應(yīng)激化合物庫 | NO PAINS 化合物庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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