Diclofenac Acyl Glucuronide NEW
| Price | $1099 |
| Package | 1mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-28 |
Product Details
| Product Name: Diclofenac Acyl Glucuronide | CAS No.: 64118-81-6 |
| Purity: 95% | Supply Ability: 10g |
| Release date: 2025/04/28 |
Product Introduction
Bioactivity
| Name | Diclofenac Acyl Glucuronide |
| Description | Diclofenac Acyl Glucuronide (Diclofenac glucuronide) is an intestinal metabolite that accelerates intestinal ulcers. |
| In vitro | Cytotoxicity and the intracellular accumulation of diclofenac acyl glucuronide were evaluated in the absence or presence of cilastatin using hOAT1/3‐transfected cells. After incubation of diclofenac acyl glucuronide for 24 hr, the survival rate of hOAT1/3‐HEK293 cells was significantly lower than that in mock‐HEK293 cells, and the IC50 values of diclofenac acyl glucuronide in hOAT1/3‐HEK293 cells were only approximately half of that in mock‐HEK293 cells[1]. |
| In vivo | Cilastatin increased the plasma concentration and decreased the renal distribution of diclofenac acyl glucuronide in mice. Diclofenac (200 mg·kg?1) was orally administered to mice. The AUC(0–12 hr) of diclofenac acyl glucuronide in plasma was increased by 46.7%, while the AUC(0–12 hr) in the kidney. [1] |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Keywords | Diclofenac Acyl Glucuronide |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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