DHODH-IN-12 NEW
Price | $117 | $175 | $268 |
Package | 1mg | 2mg | 5mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-11 |
Product Details
Product Name: DHODH-IN-12 | CAS No.: 1263303-93-0 |
Purity: 100% | Supply Ability: 10g |
Release date: 2024/11/11 |
Product Introduction
Bioactivity
名稱 | DHODH-IN-12 |
描述 | DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07. |
體外活性 | A compound structurally related to leflunomide was designed, which contained a furan ring. Compound 12a undergoes 4 ring cleavage under physiological pH conditions to obtain the corresponding cyanoxime DHODH-IN-12. DHODH-IN-12 has been analyzed as a DHODH inhibitor; its inefficiency may be due to the poor stereochemistry of the oxime substructure[1]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 60 mg/mL (295.28 mM) |
關(guān)鍵字 | DHODH-IN-12 | DHODHIN12 | DHODH IN 12 |
相關(guān)產(chǎn)品 | Disulfiram | Methotrexate | ALDH1A3-IN-3 | Rotenone | Mycophenolate Mofetil | Ribavirin | 4-Diethylaminobenzaldehyde | Benzyl alcohol | Isomalt | Isoniazid | Sodium Oxamate | Ivosidenib |
相關(guān)庫 | 經(jīng)典已知活性庫 | 抗癌細(xì)胞代謝庫 | 抑制劑庫 | 線粒體靶向庫 | 代謝化合物庫 | 已知活性化合物庫 | 共價(jià)抑制劑庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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