Dextran sulfate sodium salt (MW 4500-5500) NEW
| Price | $133 |
| Package | 5g |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-30 |
Product Details
| Product Name: Dextran sulfate sodium salt (MW 4500-5500) | CAS No.: 9011-18-1 |
| Supply Ability: 10g | Release date: 2025/04/30 |
Product Introduction
Bioactivity
| Name | Dextran sulfate sodium salt (MW 4500-5500) |
| Description | Dextran sulfate sodium salt (MW 4500-5500) is an anhydrous glucose polymer with a molecular weight range of 4500-5500. Dextran sulfate sodium salt (MW 4500-5500) inhibits human immunodeficiency virus replication by preventing viral adsorption to host cells. Dextran sulfate sodium salt (MW 4500-5500) induces inflammation mainly in the colon. It can destroy the integrity of the intestinal mucosal barrier through the high negative charge caused by sulfate groups, leading to intestinal barrier damage, macrophage dysfunction, and bacterial flora disorder. |
| In vitro | Method: Dextran Sulfate Sodium Salt (MW 4500-5500), using Dextran Sulfate Sodium Salt (MW 5000) as an example, was studied for its antiviral activity against human immunodeficiency virus type 1 (HIV-1) and its mechanism of action. MT-4 cells were exposed to different concentrations of DSS and heparin to observe their inhibitory effects on HIV-1 replication. Additionally, the cytotoxicity and impact on reverse transcriptase activity were evaluated. Results: DSS exhibited a significant selective inhibitory effect on HIV-1, with an IC50 value of 9.1 μg/ml, and showed no toxicity to host cells even at high concentrations. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : Insoluble |
| Keywords | HIVProtease | HIV Protease | HIV | Dextran sulfate sodium salt (MW 45005500) | Dextran sulfate sodium salt (MW 4500 5500) | Dextran sulfate sodium | Apoptosis |
| Inhibitors Related | Stavudine | 5-Fluorouracil | Emtricitabine | Acetylcysteine | Sodium 4-phenylbutyrate | L-Ascorbic acid | Lamivudine | L-Glutamic acid | Tributyrin | Valproic Acid | L-Ascorbic acid sodium salt | Decanedioic acid |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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