
Desvenlafaxine NEW
Price | $31 | $41 | $83 |
Package | 50mg | 100mg | 500mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: Desvenlafaxine | CAS No.: 93413-62-8 |
Purity: 99.86% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | Desvenlafaxine |
Description | Desvenlafaxine (O-Desmethylvenlafaxine) is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reuptake inhibitor (SNRI) and is used as an antidepressive agent. |
In vitro | In male rats, the oral administration of Desvenlafaxine Succinate penetrates the brain and hypothalamus, significantly increasing extracellular norepinephrine levels. |
In vivo | Desvenlafaxine Succinate inhibits the neuronal uptake of serotonin (5-HT) and norepinephrine (NE) with IC50 values of 47.3 nM and 531.3 nM, respectively. It exhibits weak binding affinity to human dopamine (DA) transporters at a concentration of 100 μM. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | Ethanol : 3 mg/mL (11.39 mM) DMSO : 16.67 mg/mL (63.28 mM), Sonication is recommended. |
Keywords | SERT | inhibit | Inhibitor | 5-HTT | Serotonin Transporter | WY45233 Succinate | SLC6A4 | Desvenlafaxine | WY-45233 Succinate |
Inhibitors Related | Alverine citrate | Dapoxetine hydrochloride | CLOZAPINE N-OXIDE | Trazodone hydrochloride | Mianserin hydrochloride | Fluoxetine hydrochloride | Cinchonidine |
Related Compound Libraries | Pain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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