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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Neuronal Signaling>5-HT Receptor modulators>Desvenlafaxine
Desvenlafaxine
  • Desvenlafaxine

Desvenlafaxine NEW

Price $31 $41 $83
Package 50mg 100mg 500mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Desvenlafaxine CAS No.: 93413-62-8
Purity: 99.86% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameDesvenlafaxine
DescriptionDesvenlafaxine (O-Desmethylvenlafaxine) is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reuptake inhibitor (SNRI) and is used as an antidepressive agent.
In vitroIn male rats, the oral administration of Desvenlafaxine Succinate penetrates the brain and hypothalamus, significantly increasing extracellular norepinephrine levels.
In vivoDesvenlafaxine Succinate inhibits the neuronal uptake of serotonin (5-HT) and norepinephrine (NE) with IC50 values of 47.3 nM and 531.3 nM, respectively. It exhibits weak binding affinity to human dopamine (DA) transporters at a concentration of 100 μM.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationEthanol : 3 mg/mL (11.39 mM)
DMSO : 16.67 mg/mL (63.28 mM), Sonication is recommended.
KeywordsSERT | inhibit | Inhibitor | 5-HTT | Serotonin Transporter | WY45233 Succinate | SLC6A4 | Desvenlafaxine | WY-45233 Succinate
Inhibitors RelatedAlverine citrate | Dapoxetine hydrochloride | CLOZAPINE N-OXIDE | Trazodone hydrochloride | Mianserin hydrochloride | Fluoxetine hydrochloride | Cinchonidine
Related Compound LibrariesPain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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