Factory Provide High Quality Desloratadine Powder CAS 100643-71-8

Introduction

Product Name :   Desloratadine 

Other name:AzoMyr;Neoclarityn;NSC 675447;Opulis;Desloratadine(Clarinex);5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro- 11-(4-piperidinylidene)-;

CAS No.: 100643-71-8

MF: C19H19ClN2

MW:310.82

Appearance: White Powder

Melting Point :150-151°C

Melting Point :467.9±45.0 °C(Predicted)

Storage :Keep in dark place,Sealed in dry,Room Temperature

Desloratadine is an antihistamine used to relieve allergy symptoms such as watery eyes, runny nose, itching eyes/nose, sneezing, hives, and itching. It works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction.

Appplication

Desloratadine is a tricyclic H1-antihistamine that is used to treat allergies. It is an active metabolite of loratadine.Desloratadine is used to treat allergic rhinitis and nasal congestion.It is the major metabolite of loratadine and the two drugs are similar in safety and effectiveness.Desloratadine is available in many dosage forms and under many trade names worldwide.

An emerging indication for desloratadine is in the treatment of acne, as an inexpensive adjuvant to isotretinoin and possibly as maintenance therapy or monotherapy.

Desloratadine is a selective H1-antihistamine which functions as an inverse agonist at the histamine H1 receptor;

It is also an antagonist at all subtypes of the muscarinic acetylcholine receptors.

It exhibits only peripheral activity since it does not readily cross the blood-brain barrier; hence, it does not cause drowsiness because it does not readily enter the central nervous system.

It has a long-lasting effect and is effective in moderate and low doses.